J Aging Health. 2025 Aug 20:8982643251369347. doi: 10.1177/08982643251369347. Online ahead of print.
ABSTRACT
Using data from the 2022 and 2023 U.S. National Aging and Health Trends Studies (N = 4,942 sample persons interviewed in both years), we examined cross-sectional and one-year lagged bidirectional relationships between the severity of cognitive impairment and depressive/anxiety symptoms. We fitted multinomial logistic and linear regression models for cross-sectional associations and a path model for one-year cross-lagged associations. Depressive/anxiety symptoms were cross-sectionally associated with a higher likelihood of both possible (mild) and probable (advanced) dementia compared to no dementia, with an even greater likelihood for probable dementia. Depressive/anxiety symptoms in 2022 were significantly associated with 2023 probable dementia, and probable dementia in 2022 was significantly associated with depressive/anxiety symptoms in 2023. The findings underscore the importance of early identification and concurrent management of both cognitive decline and depressive/anxiety symptoms in older adults.
PMID:40832717 | DOI:10.1177/08982643251369347
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