Factors associated with depressive symptoms among stroke survivors in public hospitals of Amhara regional State, Ethiopia: a multicenter cross-sectional study

Sci Rep. 2025 Sep 30;15(1):33841. doi: 10.1038/s41598-025-03847-2.

ABSTRACT

Post-stroke depression (PSD) is a prevalent condition that significantly affects stroke recovery and increases healthcare costs. Early identification of depressive symptoms and individuals at risk for PSD is crucial as it can adversely affect the prognosis of stroke recovery. Although the reported prevalence rates of post-stroke depressive symptoms vary widely across studies, evidence is scarce, particularly in Ethiopia. This study aimed to investigate the magnitude of depressive symptoms associated factors among stroke survivors. An institutional-based cross-sectional study was conducted from April 1 to Jun 30, 2022. A total of 400 participants were selected using the systematic random sampling technique. A structured interviewer-administered questionnaire was used to collect the data, and the Geriatrics Depression Scale Outcome Tool was used to assess depressive symptoms. Multicollinearity and model fitness were also assessed. Variables with a p-value of less than 0.25 in the Bivariable regression were entered into a multivariable logistic regression and a p-value of less than < 0.05 was considered statically significant. The prevalence of depressive symptoms was 47%. Balance impairment (OR = 2.58, 95% CI = 1.57-3.59), abnormal speed of mobility (OR = 2.13, 95% CI = 1.17-3.09; P ≤ 0.05), did not have physiotherapy treatment (OR = 1.97, 95% CI = 2.01, 4.95; P < 0.05), and ADL limitation (OR = 1.66, 95% CI = 0.85-2.47; P < 0.05) were significantly associated with depression symptoms. The study identified a high burden of depression symptom (47%) among stroke survivors in Ethiopia, with significant risk factors including dependent in Activity of Daily living, abnormal mobility speed, balance impairments, and lack of physical therapy participation. Clinical trial number for study was not applicable in the study. The study used Key words older adults, prevalence, post stroke, depression, and stroke burden.

PMID:41028023 | DOI:10.1038/s41598-025-03847-2