Tourette Syndrome
A nervous system disorder involving repetitive movements or unwanted sounds.
Tourette syndrome starts in childhood.
It involves uncontrollable repetitive movements or unwanted sounds (tics), such as repeatedly blinking the eyes, shrugging shoulders, or blurting out offensive words.
Treatment may include medication or psychological therapies.
Cluster Number:
Wiki Number: PW217
Diagnosis: Tourette Syndrome
US Patients: 1% of school children and adolescents
World Patients:
Sex Ratio:
Age Onset: Ages 5-7; increases to ages 8-12; then decreases for 2/3 dramatically, can have adult onset or adult recurrence from childhood
Brain Area: dysfunction in neural circuits around the basal ganglia, combines genetic and environmental factors; poor brain circuit connections
Symptoms: Motor tics and vocal tics with blinking, coughing, throat-clearing, sniffing, facial movements. Nearby muscles “urge” first for 90%
Progression: corprolalia (obscene, inappropriate or derogatory remarks) occurs in 10%,; obscene gestures may be “muscular tics” for a few
Causes: Heritable 10X-100X;forceps delivery, paternal age, pregnancy stress, tobacco, caffeine, alcohol or pot during pregnancy, premature
Medications: None
Therapies:
Youtube Video: How Tourette’s Syndrome Impacts My Life
Amazon or Library Book: Coping with Tourette Syndrome
Click the book to link or order from Amazon.
Support Group: tourette.org; 888-486-8738 (Tourette Association)
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Comorbidity of physical illnesses and mental disorders in outpatients with tic disorders: a retrospective study using the outpatient case systemby Liping Yu on December 20, 2024
CONCLUSION: Our study highlighted the most common physical diseases and mental disorders in tic disorders, namely the respiratory diseases, specifically upper respiratory tract infections, and mental and behavioral disorders, with ADHD being the most common co-occurring condition.
- Clinical Study of Limosilactobacillus reuteri for the Treatment of Children with Chronic Tic Disorders/Tourette Syndrome: A Mid-Term Efficacy Evaluationby Yan Liang on December 19, 2024
CONCLUSION: The mid-term efficacy evaluation demonstrated that L. reuteri, when added to the treatment of children with chronic TDs, was more effective in improving tic symptoms than clonidine transdermal patch treatment. Additionally, it provided moderate improvement in hyperactivity symptoms.
- Neuroanatomical and functional correlates in tic disorders and Tourette's syndrome: A narrative reviewby Anna Sara Liberati on December 18, 2024
Tic disorders represent a developmental neuropsychiatric condition whose causes can be attributed to a variety of environmental, neurobiological, and genetic factors. From a neurophysiological perspective, the disorder has classically been associated with neurochemical imbalances (particularly dopamine and serotonin) and structural and functional alterations affecting, in particular, brain areas and circuits involved in the processing and coordination of movements: the basal ganglia, thalamus,...
- Pimozide and Adipic Acid: A New Multicomponent Crystalline Entity for Improved Pharmaceutical Behaviorby Alessandra Buscarini on December 17, 2024
Pimozide is a first-generation antipsychotic used in the treatment of schizophrenia, Gilles de la Tourette syndrome, and other chronic psychoses. Its in vivo efficacy is limited by poor solubility and consequent poor bioavailability. Therefore, adipic acid was used as a coformer for the preparation of a binary product with improved pharmaceutical properties. The thermal behavior of the liquid-assisted grinding products of compositions included in the range 0.1 < X(PMZ) < 0.9 has been interpreted...