Persistent Depressive Disorder
A mild but long-term form of depression.
Dysthymia is defined as a low mood occurring for at least two years, along with at least two other symptoms of depression.
Examples of symptoms include lost interest in normal activities, hopelessness, low self-esteem, low appetite, low energy, sleep changes, and poor concentration.
Treatments include medications and talk therapy.
Cluster Number:
Wiki Number: PW161
Diagnosis: Persistent Depressive Disorder-Dysthymia
US Patients: 3-6% during lifetime
World Patients: 105 Mil per year (1.5% of the population)
Sex Ratio:
Age Onset: 21, before 21 called “early onset”
Brain Area: In women, the corpus callosum and frontal lobes differ from normal; the amygdala, insula (sadness) and cingulate gyrus(emotions)
Symptoms: 2-years for adults; 1-year for children, deep depression with longer-lasting insomnia or hypersomnia and low self-esteem
Progression: little enjoyment in anything, suicidal behaviors, other disorders or addictions; hopelessness about life
Causes: genetic for 50% of cases; 75% have other physical illnesses, disorders or addictions; 95% have episodes of major depression.
Medications: antidepressants, but 6-8 weeks before progress; SSRIs, lithium
Therapies: cognitive therapy, better sleep, exercise
Youtube Video:
Life with Persistent Depressive Disorder (also known as Dysthymia)
Amazon or Library Book: Persistent Depressive Disorders
Click the book to link or order from Amazon.
Support Group: feelingkindablue.org; 866-728-7983
(Provident Behavioral Health)
Contact your local Social Security office for possible Disability Benefits through their Disability Determination Services,
Section 12.04
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Persistent pro-inflammatory trait in elderly patients following treatment-resistant major depressive disorder: a longitudinal exploratory studyby Torfinn Lødøen Gaarden on December 3, 2024
CONCLUSION: Our findings suggest that a pro-inflammatory trait persists in elderly after an episode of treatment resistant unipolar MDD. Thus, our study supports that chronic low-grade inflammation may characterise elderly with treatment-resistant unipolar MDD.
- Functional connectivity profiles in remitted depression and their relation to ruminative thinkingby Zhuo Fang on December 2, 2024
The triple network model suggests that dysfunction in three major brain networks - the default mode network (DMN), central executive network (CEN), and salience network (SN) - might contribute to cognitive impairments in various psychiatric disorders, including major depressive disorder (MDD). While hyperconnectivity in the DMN, hypoconnectivity in the CEN, and abnormal SN connectivity have been observed in acutely depressed patients, evidence for network alterations during remission is limited....
- Role of Sleep in Depressive Disorders and the Potential Therapeutic Role of Short-Term Sleep Deprivation and Light Therapy: A Reviewby Wiktoria Bojarska on November 30, 2024
Depression affects about 280 million people globally and is marked by persistent sadness and impaired daily functioning. Sleep disturbances are prevalent in major depressive disorder, affecting roughly 90% of patients, and are linked to the severity and progression of depression. This review emphasizes the critical role of sleep in depressive disorders and evaluates the alternative treatments bright light therapy and sleep deprivation. Sleep disturbances are not only symptoms but also mediators...
- Sleep related injury and its correlates in isolated rapid eye movement sleep behavior disorderby Yuhua Yang on November 30, 2024
CONCLUSIONS: SRI is common in patients with iRBD and 18 % had pSRI despite intensive treatment, emphasizing the importance of bedside safety. The identification of risk factors for SRI and pSRI underscores the need for systematic clinical screening and targeted interventions for at-risk patients.