Parkinson’s Disease is a disorder of the central nervous system that affects movement, often including tremors.
Nerve cell damage in the brain causes dopamine levels to drop, leading to the symptoms of Parkinson’s.
Parkinson’s often starts with a tremor in one hand. Other symptoms are slow movement, stiffness, and loss of balance.
Medications can help control the symptoms of Parkinson’s.
Parkinson’s Disease is a progressive disease of the nervous system marked by tremor, muscular rigidity, and slow, imprecise movement, chiefly affecting middle-aged and elderly people. It is associated with degeneration of the basal ganglia of the brain and a deficiency of the neurotransmitter dopamine.
Wiki Number: PW153
Diagnosis: Parkinson’s Disease (Very complex; please read the Wikipedia article.)
US Patients: 2-6X likelihood of dementia
World Patients: 6.2Mil&117,400 Deaths (2015)
Age Onset: Over 60, usually; unless “early-onset Parkinson’s”
Brain Area: Cell deaths among the subantia nigra leads to dopamine deficits; Cells die from proteins into Lewy bodies in the neurons
Symptoms: tremor, slowness(bradykinesia), stiffness(excessive muscle contraction) and postural instability(10% fall weekly)
Progression: As it progresses, poor decision-making, less impulse control, impaired recall, less control of attention
Causes: genetics, injuries, pesticides;brain lesions from strokes;alpha-synuclein protein in the brain buildup; 50% have hallucinations
Medications: L-DOPA; deep brain stimulation by microelectrodes reduces muscular symptoms;
Therapies: Imaging by MRI, T2* and SW;, neuromelanin-MRI; Diffusion, MRI; PET; SPECT; DaTSCAN is the only FDA approved way to distinguish.
Youtube Video: Parkinson’s Disease: Adversity or Adventure?
Amazon or Library Book:
Parkinson’s Disease – Guide for the Newly Diagnosed
Click the book to link or buy from Amazon.
Support Group: parkinsons.org; 800-473-4636
(Parkinson’s Disease Foundation)
Support Group:michaeljfox.org; (Primarily designed to find a cure for Parkinson’s Disease. It may also have support groups.)
Contact your local Social Security office for possible Disability Benefits through their Disability Determination Services,
4 CURRENT ARTICLES
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- How Vacations Affect Parkinson's Diseaseby Jules M Janssen Daalen on January 26, 2023
- Montreal Cognitive Assessment Predicts the Short-Term Risk of Lewy Body Disease in Isolated REM Sleep Behavior Disorder with Reduced MIBG Scintigraphyby Masayuki Miyamoto on January 26, 2023
CONCLUSIONS: Among IRBD patients with reduced cardiac MIBG accumulation, MoCA-J score of <26 (Mild Cognitive Impairment-Lewy body) and a low sub-item score for delayed recall predicted short-term progression to probable DLB.
- Parkinsonism in Genetic Neurodevelopmental Disorders: A Systematic Reviewby Emma N M M von Scheibler on January 26, 2023
CONCLUSION: Parkinsonism has been reported in many GNDs. Findings from this study may provide clues for further research and improve management of patients with GNDs and/or parkinsonism.
- Activities of Daily Living Are Improved by Inpatient Multimodal Complex Treatment for PD-a Real-World Cohort Studyby Kerstin Ziegler on January 26, 2023
BACKGROUND: The multimodal complex treatment for Parkinson's disease (MCT) provides inpatient care by a multi-disciplinary team for people with Parkinson's disease (PwP) in Germany.