Nicotine Withdrawal

Millions of people know from personal experience that smoking is a tough habit to kick. The reason is that nicotine is addictive. Even though nicotine’s high isn’t as dramatic as cocaine or heroin’s, it’s equally as addictive as those illegal drugs.

And nicotine withdrawal is very real. It’s why so many smokers try many times before they finally quit for good.

Nicotine affects all areas of your body, from your heart and blood vessels to your hormones, metabolism, and brain. When you don’t have it anymore, you go through withdrawal. You’ll physically crave that nicotine hit and become irritable if you can’t have it.

Nicotine withdrawal usually lasts only a month or so, but you could be fighting the mental battle against cigarettes for a long time.

 

Cluster Number:
Wiki Number:
Diagnosis:
US Patients:
World Patients:
Sex Ratio:
Age Onset:
Brain Area: binding to nicotinic receptors in the brain, increasing dopamine; opiate, serotonic, glutamic and other receptors apply in withdrawal
Symptoms: nicotine cravings, irritability, anxiety and difficulty concentrating; symptoms usually disappear after four weeks.
Progression:
Causes: genetics may affect the severity of withdrawal
Medications: several medications can be used
Therapies: increased exercise, avoiding “smoking situations,” avoiding temptations, friend-support

Youtube Video: 72 Hours of Nicotine Withdrawal

Amazon or Library Books:
Easy Way to Quit Smoking
Easy Way to Quit Vaping 

Click the book to link or order from Amazon.

Click the book to link or order from Amazon.

4 CURRENT ARTICLES
FROM PUBMED

The world-wide medical research
reports chosen for each diagnosis 

Clicking each title opens the
PubMed article’s summary-abstract.

  • Efficacy of shared decision making in tobacco cessation among health facilities of Haryana, India - A double blinded, parallel group Randomized Controlled trial Protocol
    by Pranav Kshtriya on January 20, 2025

    BACKGROUND: Shared decision-making (SDM) incorporates evidence, patient values, and preferences into medical decision-making. SDM and decision aids might promote health professional engagement and patient knowledge of tobacco cessation therapy, improving usage and results. The SDM facilitates talks that lead to better-informed judgements that align with patients' priorities, unlike individual decision-making. Thus, the study will attempt to identify the efficacy of shared decision making in...

  • Characterization of a novel oronasal-restricted nicotine vaping self-administration model in mice
    by Lois Akinola on January 20, 2025

    Nicotine use remains one of the leading causes of preventable deaths in the United States and, while the prevalence of combustible cigarette use has declined over the past few years, the popularity of electronic nicotine delivery systems continues to rise. Vaping is not without risks, and its long-term effects, particularly in vulnerable populations, remain largely unknown. This study introduces a novel, oronasal-restricted, nicotine vapor self-administration mouse model to investigate the...

  • Incentives for smoking cessation
    by Caitlin Notley on January 12, 2025

    BACKGROUND: Financial incentives (money, vouchers, or self-deposits) can be used to positively reinforce smoking cessation. They may be used as one-off rewards, or in various schedules to reward steps towards sustained smoking abstinence (known as contingency management). They have been used in workplaces, clinics, hospitals, and community settings, and to target particular populations. This is a review update. The previous version was published in 2019.

  • The Rodent Electronic Nicotine Delivery System: Description and Validation of an Apparatus for Nose-Only E-Cigarette Aerosol Inhalation in Freely Moving Rats
    by Amy L Odum on January 7, 2025

    Tobacco use is the leading cause of death globally and in the U.S. After decades of decline, driven by decreases in combusted tobacco use, nicotine product use has increased due to Electronic Nicotine Delivery Systems (ENDS), also known as e-cigarettes or vapes. Preclinical models of nicotine self-administration can serve as important lodestars in the search for effective intervention and prevention tactics. Current variants of the task have substantial limitations, however. Therefore, we...