J Clin Endocrinol Metab. 2025 Apr 15:dgaf239. doi: 10.1210/clinem/dgaf239. Online ahead of print.
ABSTRACT
INTRODUCTION: Transitioning from pediatric to adult-centered diabetes care may be challenging, especially for young persons at risk for and with youth-onset type 2 diabetes (Y-T2D) who have a high disease burden and rapidly progressive disease. However, the scope of transition readiness, range of psychosocial factors, and perceived barriers among Y-T2D are understudied.
OBJECTIVE: In Y-T2D attending an adult diabetes transition clinic, our objectives were to: (1) characterize attitudes towards transition readiness, (2) examine relationships among depressive and anxiety-related symptoms and transition readiness, and (3) identify perceived barriers and facilitators of diabetes self-care.
METHODS: Transition readiness was assessed with the Endocrine Society “Self-assessment of Worries, Concerns, and Burdens Related to Diabetes and Preparation for Transitioning,” and mood symptoms with the Patient Health Questionnaire (PHQ-9), and the Generalized Anxiety Disorder (GAD-7) questionnaire. Logistic regression analyses evaluated the response to transition readiness by mood symptoms. Qualitative analysis identified themes of diabetes self-care in a subset of Y-T2D.
RESULTS: Survey response rate was 89%; n=65, age: 19.6±2.0y (mean±SD), 85% Y-T2D, 15% prediabetes, 57% female, 78% Black, BMI: 38.0±8.2kg/m2, and hemoglobin A1c: 7.6±2.7%. Perceived challenges were reported in 95% of participants and 54% reported worrying about their future. Mild or greater depressive and anxiety-related symptoms were associated with higher odds of reporting social, emotional, and cognitive challenges. Stress, socioeconomic difficulties, and challenges with organizational cognitive functioning were reported barriers to diabetes self-care.
CONCLUSION: Mood symptoms and difficulties with organizational cognitive functioning were commonly reported in Y-T2D during the transitioning period. Interventions are needed to successfully address these psychosocial factors.
PMID:40233175 | DOI:10.1210/clinem/dgaf239
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