Immediate risk factors for fracture recurrence after initial fractures, based on fracture liaison service dataset, and comparison with fall risk factors reported in the literature

Eur Geriatr Med. 2025 Apr 26. doi: 10.1007/s41999-025-01219-7. Online ahead of print.

ABSTRACT

INTRODUCTION: The risk of subsequent fracture is highest within 2 years of the initial fracture. This study aimed to identify risk factors for subsequent fractures in individuals aged 50 and older and compare them with those for falls, which often overlap.

METHODS: We compared 150 patients with at least two fractures (2009-2019) to 150 controls with one fracture during the same period, adjusting for age, gender, and fracture site.

RESULTS: Univariate analysis linked subsequent fractures to history of fractures (pre-2009), excessive alcohol consumption, visual or hearing impairments, cognitive disorders, rural or nursing home residency, depressive syndrome, benzodiazepine, and hypnotic use. Multivariate analysis confirmed risks for decreased visual acuity and hypnotic use.

CONCLUSION: Subsequent fracture risk is associated with falls, but not all fall risk factors increase fracture recurrence. Identifying those at risk is critical for targeted osteoporosis management within fall prevention strategies.

PMID:40285917 | DOI:10.1007/s41999-025-01219-7