Gender Dysphoria

Resources for Patients and Caregivers

Gender dysphoria: A concept designated in the DSM-5 as clinically significant distress or impairment related to a strong desire to be of another gender, which may include desire to change primary and/or secondary sex characteristics. Not all transgender or gender diverse people experience dysphoria.

 

Cluster Number:
Wiki Number: 20-Gender Dysphoria
Diagnosis: Adjustment Disorder
US Patients:
World Patients:
Sex Ratio: 
Age Onset: 
Brain Area: 
Symptoms: emotional distress over one’s assigned gender or sex
Progression: eating disorders, depression, isolation, suicide attempts
Causes:
Medications: Hormones
Therapies: transitioning psychotherapy

Youtube Video: Gender Dysphoria

Amazon or Library Book: The Gender Identity Guide for Parents

Click the book to link or order from Amazon.

  • Phenotypic spectrum and long-term outcomes of patients with 46,XX disorders of sex development
    by Heeyon Yoon on May 7, 2025

    CONCLUSION: This study described the wide phenotypic spectrum and pubertal outcome of patients with 46,XX DSD. Long-term multidisciplinary monitoring for pubertal development, fertility, gender identity, and gonadal complications is recommended.

  • Gender Minority Stressors, Hopelessness, and Their Associations with Internalizing and Externalizing Mental Health Outcomes in a Hungarian Trans Adult Sample
    by Banu C Ünsal on May 7, 2025

    Although distal (i.e., discrimination, victimization, rejection, and nonaffirmation) and proximal (i.e., internalized transphobia, negative expectations, and identity nondisclosure) gender minority stressors are associated with internalizing (i.e., depression, anxiety, suicidality) and externalizing (i.e., substance use) mental health outcomes of trans individuals, how they are related to two distinct types of outcomes differs. General psychological processes (i.e., hopelessness) could explain...

  • The intersection of the laboratory and transgender care
    by Kevin Jessen on May 2, 2025

    Transgender and gender diverse (TGD) individuals seeking gender affirming treatment are an increasing demographic in today's society; such treatments include hormonal and surgical interventions aimed at alleviating gender dysphoria and increasing quality of life. A number of diagnostic pathology tests are provided to medical professionals with sex specific reference intervals (RIs) for interpretation, due to sex specific physiological differences, organ size and hormone levels for example. These...

  • Gender inequality in immigrants' mental health: The legal status gradient
    by A Nicole Kreisberg on April 30, 2025

    Depression is a leading cause of global disease burden, and women report higher rates of depression than men. Among immigrants, gender disparities are more pronounced. But despite variation among immigrants by their legal status-which shapes correlates of mental health disorders-little is known about how and why legal status relates to gender inequalities in immigrants' depression. Using longitudinal data from the New Immigrant Survey, I find evidence that female immigrants have persistently...