Biopsychosoc Med. 2025 Jul 21;19(1):13. doi: 10.1186/s13030-025-00334-y.

ABSTRACT

BACKGROUND: Cognitive behavioral therapy for insomnia (CBT-I) has a high potential for improving insomnia and depressive symptoms; however, it is unclear whether the improvement of symptoms reaches the level of healthy people without these symptoms. We aimed to examine whether digital CBT-I can improve the insomnia and depression symptoms of workers to healthy levels.

METHODS: The study included 752 workers who were divided into four groups by the use of the cutoff scores of insomnia and depression scales: insomnia alone, depression alone, combined insomnia with depression (COMB), and healthy. All groups were administered digital CBT-I for 2 weeks, and changes were compared post-treatment and at 1- and 3-month follow-ups.

RESULTS: A significant decrease in insomnia symptoms from post-treatment to the 3-month follow-up was found in the insomnia alone (Hedges’ g: 1.07-1.52) and COMB groups (g: 1.17-1.41). The COMB group also showed a significant decrease in depressive symptoms (g: 0.38-0.70). Moreover, there were significant differences in insomnia symptoms between both of the insomnia groups and the healthy group and in depressive symptoms between the COMB group and the healthy group, post-treatment and at the 1- and 3-month follow-ups.

CONCLUSIONS: Digital CBT-I effectively reduced insomnia and depressive symptoms but did not achieve the levels of healthy people within 3 months.

TRIAL REGISTRATION: UMIN, UMIN000050353. Registered 15 February 2023-Retrospectively registered, umin.ac.jp/ctr.

PMID:40691613 | DOI:10.1186/s13030-025-00334-y