Depression
A mental health disorder characterized by persistently depressed mood or loss of interest in activities, causing significant impairment in daily life.
Possible causes include a combination of biological, psychological, and social sources of distress. Increasingly, research suggests these factors may cause changes in brain function, including altered activity of certain neural circuits in the brain.
The persistent feeling of sadness or loss of interest that characterizes major depression can lead to a range of behavioral and physical symptoms. These may include changes in sleep, appetite, energy level, concentration, daily behavior, or self-esteem. Depression can also be associated with thoughts of suicide.
The mainstay of treatment is usually medication, talk therapy, or a combination of the two. Increasingly, research suggests these treatments may normalize brain changes associated with depression.
Cluster Number:
Wiki Number: W058
Diagnoses: Depression
US Patients:
World Patients: 300Mil; 4.4%
Sex Ratio: M;W+
Age Onset:
Brain Area:
Symptoms: low mood and aversion to activity; loss of pleasure;
Effects: the leading cause of disability world-wide;
Causes: childhood adversity ,unequal treatment of siblings, abuse; adult work-or-family stress, medical diagnosis, unemployment
Medications: antidepressants should not be used with initial encounters; long-term depression can benefit from medical help
Therapies: exercise, fond memories; self-help books;
Youtube Video: “I’m Fine” Learning to Live with Depression
Amazon or Library Book:
The Upward Spiral
Amazon or Library Book:
The Vulnerable Man
Click the book to link or order from Amazon.
Click the book to link or order from Amazon.
Jim Lohr’s Download, Lifting My Depression, is available for sale
in the “Blue Box” in this website.
You can download this program from the “Blue Box”
in the right column of the website.
Support Group: dsballiance.org; 800-326-3632
(Depression and Bipolar Support Alliance)
Their website has support groups linked by zip-code
and by state; some face-to-face and some online.
Contact your local Social Security office for possible Disability Benefits through their Disability Determination Services, Section 12.04.
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- The Impact of Increased Heat on the Physical, Mental, and Social Health Domains of Adults in the United Arab Emirates in 2024by Alaa Al Hurini on January 2, 2025
CONCLUSION: Rising heat exposure in the UAE is shown to be associated with adverse effects across physical, mental, and social health domains. These findings emphasize the need for public health interventions that address not only the physical dangers of rising heat but also its psychological and social impacts. Policymakers and healthcare providers should consider comprehensive strategies to mitigate these multifaceted health risks in the face of rising temperatures.
- 6-Hydroxyflavanone treats anxiety and chemotherapy-induced neuropathy in Sprague-Dawley ratsby Shehla Akbar on January 2, 2025
CONCLUSION: 6-HF might be considered a potential therapeutic agent for counteracting two common adverse effects of chemotherapy, neurotoxicity and anxiety.
- Diploid inbred-based hybrids: fast-forward breeding approach in potatoesby Salej Sood on January 2, 2025
Following the identification of the self-compatibility gene (Sli) in diploid potatoes two decades ago, the breeding of inbred based diploid hybrid potatoes made its way. Tetraploid potatoes have a long history of cultivation through domestication and selection. Tetrasomic inheritance, heterozygosity and clonal propagation complicate genetic studies, resulting in a low genetic gain in potato breeding. Diploid hybrid TPS potato breeding, similar to the developments in hybrid maize, was pursued as...
- Depressive Symptoms and Violence Perpetration: Examining the Moderating Influence of Reward Sensitivity and Emotional Reactivity in Community Adults at Elevated Risk for Violent Behaviorby Wendy Huerta on January 2, 2025
There is growing interest in understanding whether, and under what circumstances, depression confers risk for violence perpetration. To address these questions, we examined whether major depressive disorder (MDD) symptoms correlated with violence perpetration beyond co-occurring externalizing psychopathology, and whether individual differences in reward and emotional reactivity modified depression-violence associations. In a sample of 480 community adults (M/SD (age)=32.2/10.5, 53.5% female),...