Dementia
Dementia is a collective term used to describe various symptoms of cognitive decline, such as forgetfulness. It is a symptom of several underlying diseases and brain disorders. Dementia is not a single disease in itself, but a general term to describe symptoms of impairment in memory, communication, and thinking.
Cluster Number:
Wiki Number: W055
Diagnosis: Dementia
US Patients:
World Patients: 50 Mil
Sex Ratio:
Age Onset: Age 80+- 50%
Brain Area: hippocampus shrinks; temporal and parietal lobes shrink; the brain degenerates; SPECT & PET show vascular cause.
Symptoms: early signs: handling finances, getting lost, repeating things;later-need help eating, dressing, getting out of bed
Progression: Alzheimer’s=80%; vascular, 20%=blood loss to the brain; Lewy bodies=hallucinations; frontotemporal=language problems
Causes: lewy bodies, frontotemporal dementia;people with dementia average five other chronic diseases; 50% persistent pain
Medications: donepezil, antipsychotics; no medications show a preventative effect
Therapies: exercise helps sustain activities of daily living;music; diets with low saturated fat and good carbohydrates; vitamin D
Youtube Video: Living with
Young-Onset Dementia
Youtube Video: Later Stage Dementia: Brad and Jean’s Story
Book from Amazon or Library: 2022 Dementia Overview
Click the book to link or order from Amazon.
Support Groups: alz.org; This website allows searching for
local associations. (Alzheimer’s Association)
Contact your local Social Security Office for possible Disability benefits through their Disability Determination Service,
Section 12.02.
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Multimorbidity patterns in dementia and mild cognitive impairmentby José Alejandro Valdevila Figueira on November 22, 2024
CONCLUSIONS: The study underscores the complexity of dementia and MCI in an ageing Ecuadorian population, with vascular health playing a crucial role in cognitive impairment. These findings advocate for a holistic approach in managing dementia and MCI, emphasising the importance of addressing cardiovascular and metabolic health alongside neurocognitive care. The distinct morbidity patterns identified offer insights into tailored intervention strategies, highlighting the need for comprehensive,...
- Exploring the Association Between Intravenous Lorazepam and Mortality Among Older Hospitalized Patients With and Without Cognitive Impairmentby Joseph H Flaherty on November 22, 2024
Background In a previously published study about the effects of an inpatient geriatrics program on mortality among older patients with and without cognitive impairment, intravenous (IV) lorazepam was unexpectedly found to be one of the variables associated with mortality in the multivariate analysis. The purpose of this study was to further explore the association between IV lorazepam and mortality. Materials and Methods This was a secondary data analysis of a previously published retrospective...
- Cerebrospinal fluid levels of NfM in relation to NfL and pNfH as prognostic markers in amyotrophic lateral sclerosisby Jennie Olofsson on November 22, 2024
Objective: To evaluate the prognostic potential of neurofilament medium chain (NfM) in CSF from patients with ALS and explore its relationship with the extensively studied neurofilament light chain (NfL) and phosphorylated heavy chain (pNfH). Method: CSF levels of NfL, NfM, and pNfH were analyzed in 235 samples from patients with ALS, ALS mimics, and healthy controls in a well-characterized cohort from Karolinska ALS Clinical Research Center in Stockholm, Sweden. NfM levels were analyzed using...
- How do you target cognitive training? Bridging the gap between standard and technological rehabilitation of cognitive domainsby Marina Maffoni on November 22, 2024
No abstract