Cocaine Dependence
Cocaine dependence is a biopsychosocial disorder characterized by persistent use of cocaine despite substantial harm and adverse consequences.
Cluster Number:
Wiki Number: W044
Diagnosis: Cocaine Dependence
US Patients: 6000 deaths annually
World Patients:
Sex Ratio: M;W3
Age Onset: 13-4X vs. 19
Brain Area: overdoses can constrict blood vessels in the brain and heart – causing damage
Symptoms: positively-high energy; negatively-high body temperatures, irregular heart beat, death, amphetamine psychosis,
Progression: large doses cause mood swings, paranoia, insomnia, psychosis, high blood pressure, panic attacks, cognitive impairments
Causes: 15% of users become dependent in two years
Medications: None investigated were effective.
Therapies: 12-Step Cocaine Anonymous; CBT – both have low success rates
Youtube Video: What’s Cocaine Addiction Like?
Amazon (Only on Audible), but maybe the Library has it also:
The Small Book . . Alcohol and Drug Dependence
Amazon or Library Book:
Chasing the Scream
Click the book to link or buy from Amazon.
Click the book to link or buy from Amazon.
Support Group: ca.org; Cocaine Anonymous
(Contact phone numbers are available in most states.)
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Dissociation of intake and incentive sensitization during intermittent- and continuous-access heroin self-administration in ratsby Elizabeth A Rakowski on February 20, 2025
CONCLUSIONS: These results suggest the importance of dissociating heroin intake from incentive sensitization and emphasize the significance of sex differences as a modifier of heroin consumption and motivation.
- Use of semaglutide in a 54-year-old patient with cocaine abuse and weight loss: a case reportby V M Romeo on February 18, 2025
CONCLUSION: The action of semaglutide on the hunger and reward centers offers a new approach to the treatment of patients with obesity and concomitant substance use disorders. By targeting glucagon-like peptide-1 receptors involved in both metabolic regulation and reward processing, semaglutide could potentially reduce both food intake and drug craving, thereby improving outcomes for these patients. The findings suggest that semaglutide may be a promising therapeutic option for the management of...
- Clinical and public health challenges of crack consumptionby Tiphaine Robet on February 5, 2025
Crack, the freebase form of cocaine, offers faster and more intense psychoactive effects due to its mode of administration by inhalation, while being of lower cost. These molecules act by blocking the reuptake of monoaminergic neurotransmitters, and their main effects stem from the rapid adrenergic response. The psychoactive effect is characterized by a marked surge of energy and social disinhibition. Crack consumption exacerbates the vulnerabilities of marginalized populations, requiring new...
- Phenome-wide association studies between SERINC2 and neuropsychiatric disordersby Ping Liu on February 4, 2025
CONCLUSION: SERINC2 is primarily linked to substance use disorders, schizophrenia, OCD, autism and bipolar disorder, not only statistically but also biologically.