Beneficial Effects of Apple Polyphenol Extract and Time-Restricted Feeding on Ulcerative Colitis and Accompanying Depression-like Behaviors Are Correlated with Gut-Brain Axis Modulation

J Agric Food Chem. 2025 Aug 2. doi: 10.1021/acs.jafc.5c05176. Online ahead of print. ABSTRACT Time-restricted feeding (TRF) and apple polyphenol extract (APE) emerged as promising adjuvant strategies for managing inflammation and gut microbiota imbalances. Ulcerative...