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Explainable AI reveals tissue pathology and psychosocial drivers of opioid prescription for non-specific chronic low back pain

by jlohrconsulting | Aug 22, 2025 | Uncategorized

Sci Rep. 2025 Aug 21;15(1):30690. doi: 10.1038/s41598-025-13619-7. ABSTRACT Effective management of non-specific chronic lower back pain (ns-cLBP) requires nuanced prescription decisions within evolving guidelines for conservative treatment. This study developed...

Subthreshold depression is associated with altered facial expression and impression formation via subjective ratings and action unit analysis

by jlohrconsulting | Aug 22, 2025 | Uncategorized

Sci Rep. 2025 Aug 21;15(1):30761. doi: 10.1038/s41598-025-15874-0. ABSTRACT Depression is often linked to reduced facial expressivity and to biases in recognizing others’ emotions. Whether subthreshold depression (StD)-a putative prodromal stage-shows comparable...

GDNF attenuates a-synuclein aggregation-induced damage to VTA-NAc dopaminergic transmission and alleviates depression-like behaviors in mice

by jlohrconsulting | Aug 22, 2025 | Uncategorized

Sci Rep. 2025 Aug 21;15(1):30804. doi: 10.1038/s41598-025-16556-7. ABSTRACT Dopamine (DA) transmission from the ventral tegmental area (VTA) to the nucleus accumbens (NAc) is strongly associated with depression in Parkinson’s disease (PD). Decreased DA levels...

A common neural signature between genetic and environmental risk for mental illness

by jlohrconsulting | Aug 22, 2025 | Uncategorized

Transl Psychiatry. 2025 Aug 21;15(1):305. doi: 10.1038/s41398-025-03513-1. ABSTRACT Not everyone is equally likely to experience mental illness. What is the contribution of an individual’s genetic background and experiences of childhood adversity to that...

A report of the Iranian Parkinson’s disease registry

by jlohrconsulting | Aug 22, 2025 | Uncategorized

NPJ Parkinsons Dis. 2025 Aug 21;11(1):251. doi: 10.1038/s41531-025-01108-7. ABSTRACT Millions of people worldwide suffer from Parkinson’s disease (PD), which has a varying distribution and features in each country. Since there is a shortage of data regarding PD...

Younger Dryas glacier advances in the tropical Andes driven by increased precipitation

by jlohrconsulting | Aug 22, 2025 | Uncategorized

Sci Rep. 2025 Aug 22;15(1):30832. doi: 10.1038/s41598-025-16603-3. ABSTRACT There is currently a debate about the timing and drivers of former glacier behaviour and climate change in the tropical Andes. Using 10Be dating we determined the ages of 21 boulders on...
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Recent Posts

  • Dissociative Drug-Induced Anxiety
  • Associations in intentions to use anabolic-androgenic steroids among non-consuming boys and men with probable eating disorders and muscle dysmorphia
  • Assessing schema modes for eating disorders and their association with personality traits: validation of the English version of the short form of the schema modes inventory for eating disorders (EN-SMI-ED-SF)
  • Associations in intentions to use anabolic-androgenic steroids among non-consuming boys and men with probable eating disorders and muscle dysmorphia
  • Assessing schema modes for eating disorders and their association with personality traits: validation of the English version of the short form of the schema modes inventory for eating disorders (EN-SMI-ED-SF)

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