Is the Time Right to Start Testing if Late-Onset Depression is Associated With the Development of an alpha-Synucleinopathy Like Parkinson’s Disease? A Double Systematic Review and Meta-Analysis

Am J Geriatr Psychiatry. 2025 Aug 12:S1064-7481(25)00431-2. doi: 10.1016/j.jagp.2025.07.014. Online ahead of print. ABSTRACT Parkinson’s disease (PD) is characterized by two neurobiological markers: pathological α-synuclein and/or a dopaminergic deficit....