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Ictal phase-amplitude coupling as a biomarker for seizure onset zone in neocortical epilepsy

by jlohrconsulting | Sep 19, 2025 | Uncategorized

Front Neurol. 2025 Sep 3;16:1632484. doi: 10.3389/fneur.2025.1632484. eCollection 2025. ABSTRACT OBJECTIVE: To assess ictal phase-amplitude coupling (PAC) dynamics during seizure generation and explore whether ictal PAC analysis can help identify the seizure onset...

Case Report: A case of Poirier-Bienvenu neurodevelopmental syndrome manifesting primarily as eyelid myoclonia

by jlohrconsulting | Sep 19, 2025 | Uncategorized

Front Pediatr. 2025 Sep 3;13:1583346. doi: 10.3389/fped.2025.1583346. eCollection 2025. ABSTRACT Variants in the CSNK2B gene are known to cause Poirier-Bienvenu neurodevelopmental syndrome (POBINDS). Since its first report in 2017, nearly 100 cases have been...

Inhibiting aberrant seizure-induced neurogenesis by temozolomide improves cognitive impairments associated with long-term amygdala kindling

by jlohrconsulting | Sep 19, 2025 | Uncategorized

Front Neurosci. 2025 Sep 3;19:1626118. doi: 10.3389/fnins.2025.1626118. eCollection 2025. ABSTRACT In the adult dentate gyrus, new neurons are continuously generated and integrated into the existing circuitry where they play a crucial role in maintaining important...

Systematic review and meta-analysis of executive function following remission from major depression

by jlohrconsulting | Sep 19, 2025 | Uncategorized

Biol Psychiatry Cogn Neurosci Neuroimaging. 2025 Sep 16:S2451-9022(25)00284-8. doi: 10.1016/j.bpsc.2025.09.006. Online ahead of print. ABSTRACT BACKGROUND: Executive function is significantly impaired during an acute episode of major depressive disorder (MDD)....

Fluoxetine ameliorates affective- and pain-related responses in adult zebrafish

by jlohrconsulting | Sep 19, 2025 | Uncategorized

Prog Neuropsychopharmacol Biol Psychiatry. 2025 Sep 16:111505. doi: 10.1016/j.pnpbp.2025.111505. Online ahead of print. ABSTRACT Fluoxetine, a selective serotonin reuptake inhibitor (SSRI), increases serotonin levels in the brain and modulates affective behaviors and...

Zebrafish models: Charting promising platform and illuminating the depths of depression

by jlohrconsulting | Sep 19, 2025 | Uncategorized

Pharmacol Biochem Behav. 2025 Sep 16:174097. doi: 10.1016/j.pbb.2025.174097. Online ahead of print. ABSTRACT Depression, a prevalent mental disorder with significant global health implications, remains a complex and multifaceted challenge. Despite extensive research...
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