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Case Report: Metronidazole-induced encephalopathy in a patient with acute myeloid leukemia type 2 and a literature review of the pediatric case reports

by jlohrconsulting | Oct 15, 2025 | Uncategorized

Front Pediatr. 2025 Sep 29;13:1656227. doi: 10.3389/fped.2025.1656227. eCollection 2025. ABSTRACT BACKGROUND: Metronidazole exerts neurotoxic effects on the central nervous system, leading to rare pediatric cases of metronidazole-induced encephalopathy (MIE). METHODS:...

Case Report: Implementation of stereoelectroencephalography in Kazakhstan: early experience in surgical planning for drug-resistant epilepsy

by jlohrconsulting | Oct 15, 2025 | Uncategorized

Front Hum Neurosci. 2025 Sep 29;19:1666735. doi: 10.3389/fnhum.2025.1666735. eCollection 2025. ABSTRACT INTRODUCTION: This clinical report describes the management of a 32-year-old patient with a long-standing history of drug-resistant epilepsy. It uniquely...

Postictal punctate hippocampal diffusion restriction: the chicken or the egg?

by jlohrconsulting | Oct 15, 2025 | Uncategorized

Front Neurol. 2025 Sep 29;16:1659610. doi: 10.3389/fneur.2025.1659610. eCollection 2025. ABSTRACT INTRODUCTION: Magnet resonance imaging (MRI) is the imaging gold standard for the evaluation of suspected epileptic seizures but also indispensable for detecting cerebral...

Case Report: Papillophlebitis associated with MOG-IgG-associated optic neuritis

by jlohrconsulting | Oct 15, 2025 | Uncategorized

Front Med (Lausanne). 2025 Sep 29;12:1664151. doi: 10.3389/fmed.2025.1664151. eCollection 2025. ABSTRACT Optic neuritis is a common manifestation in patients with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). However, its association with...

Adverse drug reaction profiles of histone deacetylase inhibitors

by jlohrconsulting | Oct 15, 2025 | Uncategorized

Sci Rep. 2025 Oct 14;15(1):35880. doi: 10.1038/s41598-025-19717-w. ABSTRACT The safety and tolerability of histone deacetylase inhibitors (HDACIs) were always a matter of concern. This study aimed to explore the global observational adverse drug reaction (ADR)...

The emerging landscape of brain glycosylation: from molecular complexity to therapeutic potential

by jlohrconsulting | Oct 15, 2025 | Uncategorized

Exp Mol Med. 2025 Oct 14. doi: 10.1038/s12276-025-01560-8. Online ahead of print. ABSTRACT Glycosylation functions as a pivotal posttranslational modification in proteins and as a distinct biosynthetic process in lipids. In the brain, it plays essential roles in...
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