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The emergence of genetic variants linked to brain and cognitive traits in human evolution

by jlohrconsulting | Aug 13, 2025 | Uncategorized

Cereb Cortex. 2025 Aug 1;35(8):bhaf127. doi: 10.1093/cercor/bhaf127. ABSTRACT Human evolution involved major anatomical transformations, including a rapid increase in brain volume over the last 2 million years. Examination of fossil records provides insight into these...

Pre- and postoperative pain management practices in fracture surgery: A bicentric prospective observational study in Ethiopia

by jlohrconsulting | Aug 13, 2025 | Uncategorized

Langenbecks Arch Surg. 2025 Aug 13;410(1):246. doi: 10.1007/s00423-025-03837-y. ABSTRACT BACKGROUND: Acute pain is common following orthopedic trauma and surgery. This study aims to evaluate the adequacy of pre- and postoperative pain management in traumatic fracture...

Local Regrowth After a Watch-and-Wait Strategy for Middle and Low Rectal Cancer: Is Organ Preservation Still Feasible?

by jlohrconsulting | Aug 13, 2025 | Uncategorized

Ann Surg Oncol. 2025 Aug 13. doi: 10.1245/s10434-025-18058-2. Online ahead of print. ABSTRACT BACKGROUND: The management of rectal cancer has been transformed by advances in neoadjuvant treatments, leading to complete response in approximately 30% of cases and making...

Effects of Square Stepping Exercise on Physical, Cognitive and Psychosocial Fitness in People with Parkinson’s Disease

by jlohrconsulting | Aug 13, 2025 | Uncategorized

Psychiatr Q. 2025 Aug 13. doi: 10.1007/s11126-025-10197-9. Online ahead of print. ABSTRACT Parkinson’s disease (PD) is a progressive disease characterised by motor and non-motor symptoms that affect patients’ daily activities. Square Stepping Exercise...

Postbiotics as a Therapeutic Tool in Depression: Exploring into Molecular Pathways and Neuroprotective Effects

by jlohrconsulting | Aug 13, 2025 | Uncategorized

Probiotics Antimicrob Proteins. 2025 Aug 13. doi: 10.1007/s12602-025-10703-2. Online ahead of print. ABSTRACT Depression, a debilitating mood disorder characterized by persistent sadness and anhedonia, affects millions worldwide, yet available therapies remain...

Dopamine and Mood in Psychotic Disorders: An 18F-DOPA PET Study

by jlohrconsulting | Aug 13, 2025 | Uncategorized

JAMA Psychiatry. 2025 Aug 13. doi: 10.1001/jamapsychiatry.2025.1811. Online ahead of print. ABSTRACT IMPORTANCE: There is limited neurobiological or trial evidence guiding treatment of comorbid affective syndromes in psychotic disorders. Given the use of...
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