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Combination Therapy for Platinum-Resistant Ovarian Cancer: A Novel At-Home Regimen with Envafolimab, Lenvatinib, and Etoposide

by jlohrconsulting | Jul 14, 2025 | Uncategorized

Oncologist. 2025 Jul 14:oyaf210. doi: 10.1093/oncolo/oyaf210. Online ahead of print. ABSTRACT BACKGROUND: Effective and tolerable treatment for patients with platinum-resistant recurrent ovarian cancer remains a great challenge in clinical practice. This study aimed...

Neuroimaging insights into brain mechanisms of early-onset restrictive eating disorders

by jlohrconsulting | Jul 14, 2025 | Uncategorized

Nat Ment Health. 2025;3(7):780-788. doi: 10.1038/s44220-025-00447-x. Epub 2025 Jun 24. ABSTRACT Early-onset restrictive eating disorders (rEO-ED) encompass a heterogeneous group of conditions, including early-onset anorexia nervosa (EO-AN) and avoidant/restrictive...

Neuronal activation in the paraventricular thalamus and lateral habenula during activity-based anorexia in mice

by jlohrconsulting | Jul 14, 2025 | Uncategorized

Neurosci Appl. 2024 Mar 6;3:104055. doi: 10.1016/j.nsa.2024.104055. eCollection 2024. ABSTRACT Self-starvation in anorexia nervosa patients ultimately progresses into a state of energy deficit and the body responds with homeostatic changes giving rise to many of the...

WAY-208466, a 5-HT6 receptor agonist, increases food motivation in primates: A behavioural and PET imaging study opening perspectives in eating disorders

by jlohrconsulting | Jul 14, 2025 | Uncategorized

Neurosci Appl. 2024 Aug 3;3:104086. doi: 10.1016/j.nsa.2024.104086. eCollection 2024. ABSTRACT The 5-HT6 receptor (5-HT6R) is highly expressed in the anterior striatum, a region involved in food-intake and anxiety-related behaviours that shows abnormal activity in...

To eat or not to eat: A role for ghrelin and LEAP2 in eating disorders?

by jlohrconsulting | Jul 14, 2025 | Uncategorized

Neurosci Appl. 2024 Feb 27;3:104045. doi: 10.1016/j.nsa.2024.104045. eCollection 2024. ABSTRACT Ghrelin is an orexigenic hormone that orchestrates many diverse behaviours of relevance for feeding control. It appears to operate as a hunger hormone, organizing food...

What influences food choices in anorexia nervosa? Disentangling cognitive and emotional components of decision-making by translational research

by jlohrconsulting | Jul 14, 2025 | Uncategorized

Neurosci Appl. 2024 Jun 22;3:104080. doi: 10.1016/j.nsa.2024.104080. eCollection 2024. ABSTRACT Anorexia nervosa is a serious mental illness characterized by voluntary restriction of food intake and avoidance of high-calorie food. Anxiety, highly comorbid with...
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Recent Posts

  • Dissociative Drug-Induced Anxiety
  • Associations in intentions to use anabolic-androgenic steroids among non-consuming boys and men with probable eating disorders and muscle dysmorphia
  • Assessing schema modes for eating disorders and their association with personality traits: validation of the English version of the short form of the schema modes inventory for eating disorders (EN-SMI-ED-SF)
  • Associations in intentions to use anabolic-androgenic steroids among non-consuming boys and men with probable eating disorders and muscle dysmorphia
  • Assessing schema modes for eating disorders and their association with personality traits: validation of the English version of the short form of the schema modes inventory for eating disorders (EN-SMI-ED-SF)

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