Catatonia
Cluster Number:
Wiki Number: W036
Diagnosis: Catatonia
US Patients:
World Patients:
Sex Ratio:
Age Onset:
Brain Area:
Symptoms: muscular immobility and bahavioral abnormality; may accompany schizophrenia, mental disorders, or drug withdrawals
Progression: may be rigid, mute, stay in a position or have purposeless, repetitive motions; or may be hyperactive and impulsive.
Causes: excessive glutamate with excessive movement, along with possible cell damage and death
Medications: benzodiadiazapines, electrocompulsive therapy, antipsychotics
Therapies: None given.
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4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
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PubMed article’s summary-abstract.
- A Unique Case of SCN2A Variant-Associated Catatonia and Response to Electroconvulsive Therapyby Mark Ainsley Colijn on May 16, 2024
The SCN2A gene encodes a subunit that forms part of voltage-gated sodium channels in the brain. Gain-of-function mutations are associated with epilepsy as well as numerous movement/motor abnormalities. Loss-of-function mutations may also cause epilepsy in addition to a variety of neurodevelopmental anomalies, including autism and intellectual disability. The occurrence of catatonia has also been described in 1 previous report that involved a 4-year-old boy. We describe a 20-year-old...
- The Clinical Course of a Severe Case of Malignant Catatoniaby Kalashree Gopal on May 14, 2024
Catatonia is a psychomotor syndrome predominantly associated with mental illness disorders, most commonly bipolar disorder and schizophrenia. Catatonia is classified as malignant when, in addition to catatonic symptoms, dysautonomia is present. Autonomic abnormalities can include changes in temperature, labile blood pressure, and changes in heart and respiratory rates. Because malignant catatonia is life-threatening, prompt recognition and management are essential to prevent mortality. We...
- Does serotonin reuptake inhibition provoke catatonia in patients with bipolar illness?by Nicholas Bonomo on May 14, 2024
No abstract
- Pharmacologic Treatment of Malignant Catatonia Without Electroconvulsive Therapy: A Case Reportby Conor Hegewald on May 13, 2024
Malignant catatonia is a rare, life-threatening variant of catatonia requiring prompt treatment. Malignant catatonia is characterized by typical catatonia symptoms of psychomotor, neurologic, and behavioral changes complicated by autonomic instability, with an estimated mortality rate of 50% or more when untreated. Electroconvulsive therapy (ECT) is considered the definitive and most effective treatment for malignant catatonia, with minimal literature on the efficacy of pharmacological...