Caffeine Withdrawal
Caffeine withdrawal can occur in anyone who regularly consumes caffeine and then abruptly discontinues its use. Common symptoms include headache, fatigue, low energy, irritability, anxiety, poor concentration, depressed mood and tremors, which can last anywhere from two to nine days.
Cluster Number:
Wiki Number:
Diagnosis: W032
US Patients: Caffeine (Withdrawal)
World Patients: 84% daily
Sex Ratio:
Age Onset:
Brain Area:
Symptoms: interrupts adenosine’s natural tiredness inside of the blood-brain barrier, stimulates dopamine
Progression: reduces fatigue and drowsiness; improves reaction time, concentration and motor coordination.
Causes: primary benefit 1 hour – 3-4 hours after drinking; limit 2 cups during pregnancy; 3 cups during breast-feeding
Medications: withdrawal may induce sleepiness, irritability, headache and fatigue
Therapies: reducing caffeine decreases anxiety, jitters, anxiety attacks, depression and suicide
Amazon or Library Book: Caffeine Blues
Click the book to link or order from Amazon.
Support Group: SAMHSA; 800-662-4647;
(U.S. Government, Substance Abuse &
Mental Health Services Administration)
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Prevalence, characteristics, and factors associated with caffeine-withdrawal headache during the first day of Ramadanby Rehab Magdy on March 21, 2023
CONCLUSION: Daily caffeine intake/kg body weight and caffeine use disorder are significantly associated with a caffeine-withdrawal headache.
- Effects of Chronic Administration of Green Tea Ethanol Extract on Sleep Architecture in Mice: A Comparative Study with a Representative Stimulant Caffeineby Duhyeon Kim on February 25, 2023
Wakefulness is defined as a state in which individuals can react to a change in situations. The number of people staying awake and compensating for lack of sleep has increased in recent years. Caffeine, a representative stimulant, is the most extensively consumed compound globally and is mainly consumed through coffee. Although green tea (Camellia sinensis L.) contains high caffeine content like coffee, its arousal-inducing effects have not yet been studied. In the present study, we aimed to...
- Caffeine Delays Ethanol-Induced Sedation in Drosophilaby Sonia Tremblay on January 21, 2023
Caffeine and ethanol are among the most widely available and commonly consumed psychoactive substances. Both interact with adenosine receptor-mediated signaling which regulates numerous neurological processes including sleep and waking behaviors. In mammals, caffeine is an adenosine receptor antagonist and thus acts as a stimulant. Conversely, ethanol is a sedative because it promotes GABAergic neurotransmission, inhibits glutamatergic neurotransmission, and increases the amount of adenosine in...
- Brain activity during a working memory task after daily caffeine intake and caffeine withdrawal: a randomized double-blind placebo-controlled trialby Yu-Shiuan Lin on January 18, 2023
Acute caffeine intake has been found to increase working memory (WM)-related brain activity in healthy adults without improving behavioral performances. The impact of daily caffeine intake-a ritual shared by 80% of the population worldwide-and of its discontinuation on working memory and its neural correlates remained unknown. In this double-blind, randomized, crossover study, we examined working memory functions in 20 young healthy non-smokers (age: 26.4 ± 4.0 years; body mass index: 22.7 ± 1.4...