Caffeine Dependence
Caffeine is a commonplace central nervous system stimulant drug which occurs in nature as part of the coffee, tea, yerba mate, cocoa and other plants. It is also an additive in many consumer products, most notably beverages advertised as energy drinks and colas.
Cluster Number:
Wiki Number: W031
Diagnosis: Caffeine Dependence
US Patients:
World Patients:
Sex Ratio:
Age Onset:
Brain Area: Use increases dopamine and norepinephrine
Symptoms: Stimulates reward system, but not enough to hijack it like cocaine.
Progression: Stimulating adnosine receptors induces tiredness & need to sleep;
Causes: Effects of coffee lessen and tolerance increases because the body makes more adenosine receptors.
Medications: None listed.
Therapies: Reduction in coffee to decaffinated coffee or teas. Reduce children’s soft-drink consumption.
Youtube Video: History of Coffee-Global Addiction
Amazon or Library Book: Caffeine Addiction Cure:
The Ultimate Guide to Overcome Caffeine Addiction
Click the book to link or order from Amazon.
Support Group: caffeineaddictsanonymous.com; ON-line;
(12-Step Program)
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Anti-inflammatory and antioxidant properties of Camellia sinensis L. extract as a potential therapeutic for atopic dermatitis through NF-κB pathway inhibitionby Min Jung Kim on January 18, 2025
Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by immune dysregulation and excessive cytokine production. This study aimed to explore the potential of Camellia sinensis L. water extract (CSE) as a treatment for AD by the impact of CSE on inflammatory responses in keratinocytes, particularly concerning the production of inflammatory cytokines and the modulation of signaling pathways relevant to AD pathogenesis. CSE was obtained via hot water extraction from Camellia...
- Atmospheric Pressure Mass Spectrometry Imaging Using Electrospray-Assisted Laser Desorption/Ionization with Gas Transportation through a Heated Tube and Minimal Sample Preparationby Riku Hirotani on January 8, 2025
Mass spectrometry (MS) is a valuable tool that enables label-free analysis and the ability to measure multiple molecules. The atmospheric pressure MS imaging (MSI) method usually requires tedious sample preparation. A simple ionization method with minimal sample preparation is needed for high-throughput analysis. We have developed an ion source that does not require sample preparation such as thinning, curing, planarization, or addition of matrix by the electrospray-assisted laser...
- Comparative effects of arecoline, caffeine, and nicotine on transcription level in the nucleus accumbens of miceby Shaofang Huang on January 6, 2025
Though widely consumed, current research on the neural mechanisms of arecoline, caffeine, and nicotine remains limited, and the similarities and differences of these substances on the nervous system are still not clear. This study used RNA-seq to analyze the gene expression in the nucleus accumbens (NAc) of mice, and compared the behavioral changes through open field and conditioned place preference (CPP), exploring the effects of different psychoactive substances at transcriptional and...
- Ca²⁺ signaling in myenteric interstitial cells of Cajal (ICC-MY) and their role as conditional pacemakers in the colonby Salah A Baker on January 4, 2025
Interstitial cells of Cajal in the plane of the myenteric plexus (ICC-MY) serve as electrical pacemakers in the stomach and small intestine. A similar population of cells is found in the colon, but these cells do not appear to generate regular slow wave potentials, as characteristic in more proximal gut regions. Ca^(2+) handling mechanisms in ICC-MY of the mouse proximal colon were studied using confocal imaging of muscles from animals expressing GCaMP6f exclusively in ICC. ICC-MY displayed...