CONCLUSIONS: Incorporating the high-level MSN_II based on radiomics features can improve the classification performance compared to models solely relying on GMV features alone. This result implied the potential application of the proposed high level MSN method and radiomics textural features on the MDD and BD clinical studies.

CONCLUSION: The results obtained indicate less functional impairment and a better perception of QoL when compared to literature data, demonstrating that there is a subgroup of caregivers who perform their caregiving role without significant compromise in these health aspects. Exploring other factors associated with functionality and QoL, such as resilience, the presence of psychological support, or others, may allow for better targeting of public health interventions, optimizing comprehensive...

CONCLUSIONS: Our findings suggest that women with BD with a history of premenstrual symptoms and postpartum depression are potentially at increased risk of experiencing episodes of depression in relation to the perimenopause. There are clinical and self-management implications in identifying a subgroup of women with BD who may be particularly vulnerable to episodes of mood disturbance during reproductive events.

A strict association exists between mood disorders and endogenous hypercortisolism, namely Cushing's syndrome (CS). Indeed, CS is characterized by a wide range of mood disorders, such as major depression, generalized anxiety, panic disorders, bipolar disorders up to psychosis, with major depression being the most frequent, with a prevalence of 50-80%, and potentially representing the clinical onset of disease. Despite this observation, the exact prevalence of hypercortisolism in patients with...