Bipolar I
Resources for Patients and Caregivers
Bipolar I Disorder— defined by manic episodes that last at least 7 days, or by manic symptoms that are so severe that the person needs immediate hospital care. Usually, depressive episodes occur as well, typically lasting at least 2 weeks.
Cluster Number:
Wiki Number: 08-Bipolar I
Diagnosis: This requires just one full manic episode where the individual may be “high” for several days.
US Patients: 1% of the US population in their lifetimes.
World Patients:
Sex Ratio:
Age Onset:
Brain Area:
Symptoms: Typically it will be followed by one or more depressive stretches of time.
Progression: Relatively good, may last 6 months or 25% go to PTSD or Major Depressive Disorder
Causes:
Medications:Can be reduced by other prescribed drugs.
Therapies:
Youtube Video: Faces of Bipolar Disorder (PART 2) “Bipolar Type 1”
Amazon or Library Book: Bipolar Disorder 1
How to Survive and Thrive
Click the book to link or order from Amazon.
Support Group: dsballiance.org; 800-326-3632
(Depression and Bipolar Support Alliance)
Contact your local Social Security offic for possible Disability Benefits through their Disability Determination Services,
Section 12.04.
Resources for Physicians, Counselors and Researchers
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Methylation of SSTR4 promoter region in multiple mental health disordersby Rongrong Zhao on July 26, 2024
The existence of a shared genetic basis for mental disorders has long been documented, yet research on whether acquired epigenetic modifications exhibit common alterations across diseases is limited. Previous studies have found that abnormal methylation of cg14631053 at the SSTR4 promoter region mediates the onset of alcohol use disorder. However, whether aberrant methylation of the SSTR4 gene promoter is involved in other mental health disorders remains unclear. In this study, leveraging...
- Exploration of Nursing Care for Individuals With Bipolar Disorder in a Manic Episode: A Qualitative Studyby Evangelos C Fradelos on July 26, 2024
CONCLUSIONS: Nursing care plays an important role in symptom improvement and disease control by providing patient support, managing pharmacotherapy, preventing suicidality, and educating patients about the disease and self-management strategies.
- Cross-species single-cell landscapes identify the pathogenic gene characteristics of inherited retinal diseasesby Hualei Hu on July 26, 2024
CONCLUSION: We identified molecular pathways and cell types closely connected with IRDs, bridging the gap between gene expression, genetics, and pathogenesis. The IRD genes enriched in cell-specific modules and regulons suggest that these diseases share common etiological bases. Overall, mining of interspecies transcriptome data reveals conserved transcriptomic features of retinas across species and promising applications in both normal retina anatomy and retina pathology.
- Molecular mechanisms and therapeutic potential of lithium in Alzheimer's disease: repurposing an old class of drugsby Yanxin Shen on July 26, 2024
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory loss. Despite advances in understanding the pathophysiological mechanisms of AD, effective treatments remain scarce. Lithium salts, recognized as mood stabilizers in bipolar disorder, have been extensively studied for their neuroprotective effects. Several studies indicate that lithium may be a disease-modifying agent in the treatment of AD. Lithium's neuroprotective properties in...