Autism Spectrum Disorder

A serious developmental disorder that impairs the ability to communicate and interact.
Autism spectrum disorder impacts the nervous system.
The range and severity of symptoms can vary widely. Common symptoms include difficulty with communication, difficulty with social interactions, obsessive interests, and repetitive behaviors.
Early recognition, as well as behavioral, educational, and family therapies may reduce symptoms and support development and learning.

 

Cluster Number:
Wiki Number: W017
Diagnosis: Autism Spectrum Disorder
US Patients: 1.5Mil
World Patients: 62Mil
Sex Ratio: 4B;1G
Age Onset: By 1
Brain Area: Enlarged frontal and temporal lobes, mirrror neurons, corpus callosum
Symptoms: poor communication, repetitive behaviors
Progression: delayed language & cognitive development; 50% head banging, self-biting;10% savants
Causes: 75% genetic from 1000 genes; not enough GABA, less brain connectivity between regions
Medications: risperdone
Therapies: earlier, the better; teach coping skills, awareness of others’ presence, interests

Youtube Video: Meet the Experts:

Autism Explained: A Guide to Autism

Amazon or Library Book: Kids With Autism Spectrum Disorder

Amazon or Library Book: Parenting a Child with Autism

Click the book to link or order from Amazon.

Click the book to link or order from Amazon.

Contact your school for Special Education under the

U.S. Department of Education’s Individuals with

Disabilities Education Act, Section 300.8.

Contact your local Social Security office for possible Disability Benefits through their Disability Determination Services, Section12.10.

4 CURRENT ARTICLES
FROM PUBMED

The world-wide medical research
reports chosen for each diagnosis 

Clicking each title opens the
PubMed article’s summary-abstract.

  • Bilingualism Effects in Metaphor and Simile Comprehension and Production in Children With Autism Spectrum Disorder
    by Maria Andreou on February 22, 2025

    Figurative language, including metaphors and similes, is a crucial component of communication; yet, it presents significant challenges for individuals with autism spectrum disorder (ASD). A critical gap in existing research is the impact of bilingualism on the ability of children with ASD to understand and produce non-literal speech. This study addresses this gap by examining the comprehension and production of metaphors and similes in monolingual and bilingual Greek-speaking children with...

  • The epilepsy-autism phenotype associated with developmental and epileptic encephalopathies: New mechanism-based therapeutic options
    by Nicola Specchio on February 22, 2025

    Epilepsy and autism often co-occur in genetic developmental and epileptic encephalopathies (DEEs), but their underlying neurobiological processes remain poorly understood, complicating treatment. Advances in molecular genetics and understanding the neurodevelopmental pathogenesis of the epilepsy-autism phenotype may lead to mechanism-based treatments for children with DEEs and autism. Several genes, including the newly reported PPFIA3, MYCBP2, DHX9, TMEM63B, and RELN, are linked to various...

  • Cerebellar Alterations in Autism Spectrum Disorder: A Mini-Review
    by Bianca Andrade Rodrigues on February 22, 2025

    Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by difficulties in social communication and restricted and repetitive patterns of behavior. In addition, individuals diagnosed with ASD may also present cognitive impairments. The neurobiological mechanisms possibly associated with the cause of ASD have not yet been fully elucidated. Studies suggest that brain alterations, especially in the cerebellum, play a fundamental role in the etiology of ASD. This brain region,...

  • Mercury exposure and childhood outcomes: an overview of systematic reviews
    by Lauren E O'Connor on February 22, 2025

    CONCLUSION AND RELEVANCE: Mercury exposure during pregnancy and childhood is recognized as a major public health concern. However, more research is needed that specifically examines methylmercury from seafood to better inform future dietary recommendations.