Association Between Serum Uric Acid/Creatinine Ratio and Depressive Symptoms in Middle-Aged and Older Adults: Evidence from Two Large Population-Based Studies in China and the United States

Int J Psychiatry Med. 2025 Sep 30:912174251384015. doi: 10.1177/00912174251384015. Online ahead of print. ABSTRACT ObjectiveEmerging evidence suggests that serum uric acid (SUA) can modulate depressive symptoms, potentially via mechanisms involving oxidative stress....