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Adverse drug reaction profiles of histone deacetylase inhibitors

by jlohrconsulting | Oct 15, 2025 | Uncategorized

Sci Rep. 2025 Oct 14;15(1):35880. doi: 10.1038/s41598-025-19717-w. ABSTRACT The safety and tolerability of histone deacetylase inhibitors (HDACIs) were always a matter of concern. This study aimed to explore the global observational adverse drug reaction (ADR)...

The emerging landscape of brain glycosylation: from molecular complexity to therapeutic potential

by jlohrconsulting | Oct 15, 2025 | Uncategorized

Exp Mol Med. 2025 Oct 14. doi: 10.1038/s12276-025-01560-8. Online ahead of print. ABSTRACT Glycosylation functions as a pivotal posttranslational modification in proteins and as a distinct biosynthetic process in lipids. In the brain, it plays essential roles in...

Beyond motor neurons: autonomic dysfunction and ECG findings in adults with 5q-spinal muscular atrophy

by jlohrconsulting | Oct 15, 2025 | Uncategorized

J Neurol. 2025 Oct 14;272(10):694. doi: 10.1007/s00415-025-13446-w. ABSTRACT BACKGROUND: 5q-Spinal muscular atrophy (SMA) is a lower motor neuron disease. However, peripheral organ involvement might contribute to its complex clinical picture, especially in severe...

Prefrontal and parieto-occipital neural signatures of evidence accumulation and response to computerised Cognitive Behavioural Therapy in depression

by jlohrconsulting | Oct 15, 2025 | Uncategorized

Npj Ment Health Res. 2025 Oct 14;4(1):51. doi: 10.1038/s44184-025-00165-3. ABSTRACT Computerised Cognitive Behavioural therapy (CBT) is an effective psychological intervention for mild to moderate depression. While CBT aims to correct maladaptive cognitive biases and...

Mental Health and Interoceptive Sensibility in Inherited Cardiovascular Conditions: A Clinical Investigation of Psychological and Behavioural Correlates

by jlohrconsulting | Oct 15, 2025 | Uncategorized

Int J Behav Med. 2025 Oct 14. doi: 10.1007/s12529-025-10404-8. Online ahead of print. ABSTRACT BACKGROUND: Integrated care models that address both the physical and psychological needs of patients with inherited cardiovascular conditions (ICCs) are increasingly...
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Recent Posts

  • Dissociative Drug-Induced Anxiety
  • Associations in intentions to use anabolic-androgenic steroids among non-consuming boys and men with probable eating disorders and muscle dysmorphia
  • Assessing schema modes for eating disorders and their association with personality traits: validation of the English version of the short form of the schema modes inventory for eating disorders (EN-SMI-ED-SF)
  • Associations in intentions to use anabolic-androgenic steroids among non-consuming boys and men with probable eating disorders and muscle dysmorphia
  • Assessing schema modes for eating disorders and their association with personality traits: validation of the English version of the short form of the schema modes inventory for eating disorders (EN-SMI-ED-SF)

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