Sage Open Aging. 2025 Aug 20;11:30495334251366009. doi: 10.1177/30495334251366009. eCollection 2025 Jan-Dec.
ABSTRACT
OBJECTIVE: To determine the association between depressive symptoms and cognitive impairment in patients over 75 years of age in the High Andean communities of Peru.
PATIENTS AND METHODS: A retrospective cross-sectional study was conducted. The sample consisted of 181 older adults. The Yesavage Test was used for depression screening (5-item version), and the Pfeiffer questionnaire was used for cognitive impairment screening. Poisson regression with robust variance was used to determine the association between variables with a 95% confidence level. The analyses were performed using STATA 16.
RESULTS: About 63.54% were female, with an average age of 79.52 ± 4.21 years. About 43.6% showed cognitive impairment, of which 29.8% were mild and 13.26% were moderate. An association was found between depression and cognitive impairment (p < .001; aPR = 4.70, 95% CI [2.25, 9.79]).
CONCLUSION: There is an association between depressive symptoms and cognitive impairment in older adults from high Andean communities in Peru.
PMID:40852421 | PMC:PMC12368311 | DOI:10.1177/30495334251366009
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