Asperger’s Syndrome

A developmental disorder affecting ability to effectively socialize and communicate.
Asperger syndrome is a condition on the autism spectrum, with generally higher functioning.

People with this condition may be socially awkward and have an all-absorbing interest in specific topics.

Communication training and behavioral therapy can help people with the syndrome learn to socialize more successfully.


Cluster Number:
Wiki Number: W015
Diagnosis: Asperger’s Syndrome
US Patients:
World Patients: 37Mil;½of1%
Sex Ratio: B+;G
Age Onset: Age1-2
Brain Area: poor neural connections, lack of “mirror neurons” for others’ behaviors
Symptoms: poor social Interactions, restricted interests, rigid mobility
Progression: Lifetime, train for social interactions and fewer repeated activities
Causes: Heredity
Medications: At present, only co-morbid difficulties are medicated effectively.
Therapies: none currently, but the children are usually quite high-functioning


The world-wide medical research
reports chosen for each diagnosis 

Clicking each title opens the
PubMed article’s summary-abstract.

  • Reversible splenial lesion syndrome with mental disorders as only manifestation
    by Ziyun Xu on September 16, 2021

    CONCLUSIONS: We found that RESLES might only showed mental symptoms. On the one hand, for the patients with acute mental disorders, clinicians should be alert to the possibility of RESLES caused by physical disease. On the other hand, we suggest that mental disorder might be a precipitating factor of RESLES.

  • Mentalization-Based Treatment in Groups for Adults With Autism Spectrum Disorder
    by Katharina Krämer on August 30, 2021

    In order to successfully interact with others in social encounters, we have to be attentive to their mental states. This means, we have to implicitly and explicitly interpret our own actions as well as the actions of others as meaningful on the basis of the ascription of intentional mental states. However, this ability, often referred to as mentalizing, seems to be impaired in autism spectrum disorder (ASD). Individuals with ADS show specific deficits relating to the representation of mental...

  • The Autism-Spectrum Quotient (AQ) Adolescent's Version in Turkey: Factor Structure, Reliability and Validity
    by Elif Cetinoglu on August 30, 2021

    We assessed the reliability and validity of the Turkish version of the autism spectrum quotient (AQ)-adolescent. Three assessment groups of adolescents, aged 11-18, were: 80 with Asperger syndrome/high-functioning autism (AS/HFA), 71 with other psychiatric disorders (PDs; 35 major depression, 18 obsessive-compulsive disorder, 18 social phobia), and 249 healthy controls. The scores of the AS/HFA group were significantly higher than the healthy control and PD groups. Cronbach α value was 0.829....

  • Early Motor Skills in Children With Autism Spectrum Disorders Are Marked by Less Frequent Hand and Knees Crawling
    by Nathalie Lavenne-Collot on August 10, 2021

    Our aim in this study was to affirm or negate (quantitatively) our subjective impression of altered hands and knees crawling (H&K crawling) among children with Autism Spectrum Disorder (ASD). Through parental questionnaires and children's health records, we retrospectively compared early motor skills, including the frequency of H&K crawling in 79 children with Autistic Disorder or Asperger Syndrome versus 100 children with typical development (TD). We found H&K crawling to be significantly less...