Antidepressant Discontinuation Syndrome
Resources for Patients and Caregivers
Typical symptoms of antidepressant discontinuation syndrome include flu-like symptoms, insomnia, nausea, imbalance, sensory disturbances, and hyperarousal. These symptoms usually are mild, last one to two weeks, and are rapidly extinguished with reinstitution of antidepressant medication.
Wiki Number: 06-Antidepressant Discontinuation Syndrome
Diagnosis: After a month of antidepressants sudden stops or even tapering off take a week to a year.
Brain Area: Antidepressants apparently reorganize the neurotransmitters, serotonin, dopamine, etc.
Symptoms: Flu-like, disturbed sleep and/or balance, nausea or sensory changes.
Progression: Occurs in 20-50% of stopping use of antidepressants, especially when stopped immediately.
Youtube Video: Antidepressant Withdrawal
Amazon or Library Book: The People’s Safety Guide to Antidepressants
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Resources for Physicians, Counselors and Researchers
4 CURRENT ARTICLES
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Adverse Effects of Antidepressant Medications and their Management in Children and Adolescentsby Jeffrey R Strawn on January 18, 2023
Selective serotonin reuptake inhibitors (SSRIs) and, to a lesser extent, serotonin-norepinephrine reuptake inhibitors (SNRIs) are the cornerstone of pharmacotherapy for children and adolescents with anxiety and depressive disorders. These medications alleviate symptoms and restore function for many youths; however, they are associated with a distinct adverse effect profile, and their tolerability may complicate treatment or lead to discontinuation. Yet, SSRI/SNRI tolerability has received...
- Maintenance Electroconvulsive Therapy, Developmental Regression, Depression and Catatonia in an Adolescent With Down Syndrome: A Case Reportby Gameli Anthonio on December 29, 2022
This is a case report involving a 22-year-old male with a past medical history of Down syndrome and major depressive disorder who, at age 16, became preoccupied with returning to an infant-like state. He experienced a gradual deterioration in his mood over a year and began to show symptoms consistent with catatonia. These symptoms included waxy flexibility, hypokinesis, decreased appetite, mutism, and altered sleep habits. Pharmacologic therapy was initiated, and the patient experienced a waxing...
- Short-course antidepressant therapy reduces discontinuation syndrome while maintaining treatment efficacy in patients with refractory functional dyspepsia: A randomized controlled trialby Qian-Qian Wang on December 26, 2022
CONCLUSIONS: Compared to 4-week FM therapy, the 2-week FM therapy reduces the risk of ADS with non-inferior treatment efficacy in patients with rFD.
- Restless Legs Syndrome After Aripiprazole Discontinuation: A Case Report and Review of Literatureby Gonca Dokuz on December 22, 2022