Antidepressant Discontinuation Syndrome

Resources for Patients and Caregivers

Typical symptoms of antidepressant discontinuation syndrome include flu-like symptoms, insomnia, nausea, imbalance, sensory disturbances, and hyperarousal. These symptoms usually are mild, last one to two weeks, and are rapidly extinguished with reinstitution of antidepressant medication.


Cluster Number:
Wiki Number: 06-Antidepressant Discontinuation Syndrome
Diagnosis: After a month of antidepressants sudden stops or even tapering off take a week to a year.
US Patients:
World Patients:
Sex Ratio:
Age Onset: 
Brain Area: Antidepressants apparently reorganize the neurotransmitters, serotonin, dopamine, etc.
Symptoms: Flu-like, disturbed sleep and/or balance, nausea or sensory changes.
Progression: Occurs in 20-50% of stopping use of antidepressants, especially when stopped immediately.

Youtube Video: Antidepressant Withdrawal

Amazon or Library Book: The People’s Safety Guide to Antidepressants

Click the book to link or order from Amazon.

Resources for Physicians, Counselors and Researchers


The world-wide medical research
reports chosen for each diagnosis 

Clicking each title opens the
PubMed article’s summary-abstract.