Antidepressant Discontinuation Syndrome
Resources for Patients and Caregivers
Typical symptoms of antidepressant discontinuation syndrome include flu-like symptoms, insomnia, nausea, imbalance, sensory disturbances, and hyperarousal. These symptoms usually are mild, last one to two weeks, and are rapidly extinguished with reinstitution of antidepressant medication.
Cluster Number:
Wiki Number: 06-Antidepressant Discontinuation Syndrome
Diagnosis: After a month of antidepressants sudden stops or even tapering off take a week to a year.
US Patients:
World Patients:
Sex Ratio:
Age Onset:
Brain Area: Antidepressants apparently reorganize the neurotransmitters, serotonin, dopamine, etc.
Symptoms: Flu-like, disturbed sleep and/or balance, nausea or sensory changes.
Progression: Occurs in 20-50% of stopping use of antidepressants, especially when stopped immediately.
Causes:
Medications:
Therapies:
Youtube Video: Antidepressant Withdrawal
Amazon or Library Book: The People’s Safety Guide to Antidepressants
Resources for Physicians, Counselors and Researchers
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Effect of selective serotonin reuptake inhibitor discontinuation on anxiety-like behaviours in miceby Helen M Collins on May 24, 2022
CONCLUSION: Overall, this study provides evidence for a short-lasting behavioural discontinuation response to cessation of SSRI treatment in mice.
- Treating Severe Refractory and Augmented Restless Legs Syndromeby John W Winkelman on May 24, 2022
Restless legs syndrome (RLS) is a sensory-motor neurologic disorder present to a clinically significant degree in 2% to 3% of the adult population, more commonly with advancing age and in women, that dramatically affects sleep and quality of life. Addressing factors that worsen RLS (eg, iron deficiency, antidepressant or antihistamine administration, OSA) is an important first step in treatment. RLS can generally be well treated with medications such as the alpha(2)-delta calcium channel ligands...
- Antidepressant-induced serotonin syndrome in older patients: a cross-sectional studyby Neziha Erken on May 13, 2022
CONCLUSIONS: The widespread single or combined use of antidepressants in older adults represents an increased clinical concern for SS and physicians should be aware of this drug-related complication in older patients.
- Restless Legs Syndrome Due to the Use of Trazodone: A Case Reportby Barış Yilbaş on March 28, 2022
Many case reports have demonstrated that using antidepressants and especially the selective serotonin reuptake inhibitors (SSRIs), and the noradrenergic and specific serotonergic antidepresants mirtazapine and mianserin can lead to restless legs syndrome (RLS). However, there are disagreements in the results of the limited number of investigations on the relationship of RLS with antidepressants. Trazodone is a frequently used antidepressant with complex agonistic/antagonistic effects on the...