Alzheimer’s Disease
A progressive disease that destroys memory and other important mental functions.
Brain cell connections and the cells themselves degenerate and die, eventually destroying memory and other important mental functions.
Memory loss and confusion are the main symptoms.
No cure exists, but medications and management strategies may temporarily improve symptoms.
Cluster Number:
Wiki Number: W007
Diagnosis: Alzheimer’s Disease
US Patients:
World Patients: 30Mil
Sex Ratio: M; 3F
Age Onset: 65+to42% by 80+
Brain Area: hippocampus, amyloids & tau proteins, 19 genes
Symptoms: forgetting, poor short term memory, location confusion
Progression: poor thinking, repetitious conversations, abusive, anxious, paranoid, loses ability to live
Causes: 19 genes, head injuries, depression, hypertension, smoking
Medications: memantine, acetylcholinemesterase inhibitors
Therapies: Chess, book-reading, exercise;low-fat diet, caffeine, wine
Youtube Video: Alzheimer’s Disease-Early Signs
Amazon or Library Book:
Is It Alzheimer’s?
Amazon or Library Book:
36-Hour Day
Click the book to link or order from Amazon.
Click the book to link or order from Amazon.
Support Group: Alzheimer’s Association 800-272-3900
Contact your local Social Security office for possible Disability Benefits through their Disability Determination Services,
Section 12.02.
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Long-Term Multimodal Exercise Intervention for Patients with Frontotemporal Lobar Degeneration: Feasibility and Preliminary Outcomesby Miyuki Nemoto on January 22, 2025
CONCLUSION: The long-term multimodal exercise intervention may be feasible and positively change the cognitive, psychological, physical, and behavioral functions in older adults with FTLD. Although the intervention led to improvements in certain areas, there were also declines observed in various functions, which may not necessarily be due to the intervention itself but rather reflect the natural progression of the disease.
- Threshold effects of sleep duration and cognitive function in older adults with BMI ≥ 25 kg/m2by Kunyu Qiu on January 22, 2025
CONCLUSION: In overweight and obese older adults, there is a clear inverted U-shaped relationship between sleep duration and cognitive function, with consistent results across different subgroups. Sleep durations of around 5-6 h may help prevent cognitive decline in older adults with a BMI ≥ 25 kg/m².
- Association between osteoarthritis and cognitive function: results from the NHANES 2011-2014 and Mendelian randomization studyby Kun Zhao on January 22, 2025
CONCLUSION: Our findings indicate that there is no significant association or causal relationship between OA and cognitive decline. However, depression may serve as an important factor influencing cognitive outcomes. Future research should further explore the bidirectional causal relationship and underlying mechanisms.
- Deep learning captures the effect of epistasis in multifactorial diseasesby Vladislav Perelygin on January 22, 2025
CONCLUSION: Overall, our study underscores the efficacy of non-linear models and deep learning approaches in more accurately accounting for the effects of epistasis in simulations with specific configurations and in the context of certain diseases.