Alcoholism
A chronic disease characterized by uncontrolled drinking and preoccupation with alcohol.
Alcoholism is the inability to control drinking due to both a physical and emotional dependence on alcohol.
Symptoms include a strong need or urge to use alcohol. Those with alcohol use disorder may have problems controlling their drinking, continue to use alcohol even when it causes problems, or have withdrawal symptoms when they rapidly decrease or stop drinking.
Treatment involves counseling, such as behavioral therapy, and medications that reduce the desire to drink. Some people need medical detoxification to stop drinking safely. Mutual support groups help people stop drinking, manage relapses and cope with necessary lifestyle changes.
Cluster Number:
Wiki Number: W0004
Diagnosis: Alcoholism
US Patients: 2016-5.1%
World Patients: 380Million
Sex Ratio: 2M-1F
Age Onset:
Brain Area:
Symptoms: Overstimulation of GABA receptors
Progression: increasing drinking
Causes: Cirrhosis of the liver, epilesy, cancer; dementia, women more likely
Medications: Acamprosate, naltrexone, opoids,
Therapies: Alcoholics Anonymous and 12-Step programs
Youtube Video: Warning Symptoms of Alcoholism
Amazon or Library Book:
Understanding Alcoholism as a Brain Disease
Click the book to link or order from Amazon.
Support Group: Alcoholics Anonymous-aa.org
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- TEC-mediated tRF-31R9J regulates histone lactylation and acetylation by HDAC1 to suppress hepatocyte ferroptosis and improve non-alcoholic steatohepatitisby Juanjuan Zhu on January 22, 2025
CONCLUSIONS: This study demonstrates that TEC-mediated tRF-31R9J inhibits hepatocyte ferroptosis through HDAC1-regulated histone delactylation and deacetylation, thereby improving NASH. These discoveries offer a theoretical foundation and new strategies for the medical management of NASH.
- NAFPD exacerbation by hyperlipidemia combined with hyperuricemia: a pilot rat experiment in lipidomicsby Jingyun Li on January 22, 2025
CONCLUSION: Hyperlipidemia combined with hyperuricemia might exacerbates NAFPD. Glycerophospholipids may serve as key biomarkers in this process, potentially linked to a chronic inflammatory response mediated by glycerophospholipids.
- Non-alcoholic fatty liver disease is a strong predictor of carotid high-risk plaques as assessed by high-resolution magnetic resonance imagingby Tianqi Xu on January 22, 2025
CONCLUSIONS: NAFLD is associated with carotid HRP as assessed by high-resolution MRI. CT-defined NAFLD may be a novel and robust predictor for identifying HRP.
- The relationship between anthropometric indices and non-alcoholic fatty liver disease in adults: a cross-sectional studyby Mina Radmehr on January 22, 2025
CONCLUSION: Based on the findings, BMI and WHtR emerge as the most practical and accessible indicators for early screening of NAFLD in both men and women, while ABSI shows minor effectiveness in identifying the disease.