Alcoholism
A chronic disease characterized by uncontrolled drinking and preoccupation with alcohol.
Alcoholism is the inability to control drinking due to both a physical and emotional dependence on alcohol.
Symptoms include a strong need or urge to use alcohol. Those with alcohol use disorder may have problems controlling their drinking, continue to use alcohol even when it causes problems, or have withdrawal symptoms when they rapidly decrease or stop drinking.
Treatment involves counseling, such as behavioral therapy, and medications that reduce the desire to drink. Some people need medical detoxification to stop drinking safely. Mutual support groups help people stop drinking, manage relapses and cope with necessary lifestyle changes.
Cluster Number:
Wiki Number: W0004
Diagnosis: Alcoholism
US Patients: 2016-5.1%
World Patients: 380Million
Sex Ratio: 2M-1F
Age Onset:
Brain Area:
Symptoms: Overstimulation of GABA receptors
Progression: increasing drinking
Causes: Cirrhosis of the liver, epilesy, cancer; dementia, women more likely
Medications: Acamprosate, naltrexone, opoids,
Therapies: Alcoholics Anonymous and 12-Step programs
Youtube Video: Warning Symptoms of Alcoholism
Amazon or Library Book:
Understanding Alcoholism as a Brain Disease
Click the book to link or order from Amazon.
Support Group: Alcoholics Anonymous-aa.org
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Copper status and its relation to abdominal obesity indices and liver function in non-alcoholic fatty liver disease: a case-control studyby Sara Arefhosseini on December 20, 2024
OBJECTIVE: This study investigated copper (Cu) status in relation to abdominal obesity indices and liver function in patients with non-alcoholic fatty liver disease (NAFLD). This case-control study was carried out on 80 overweight/obese patients with NAFLD and 80 apparently healthy age, sex, and body mass index (BMI)-matched controls. A validated and reliable 168-item semi-quantitative food frequency questionnaire was completed for each subject and fasting serum levels of liver...
- Association between composite dietary antioxidant index and metabolic dysfunction-associated fatty liver disease: a cross-sectional study from NHANESby Jia-Xin Dong on December 20, 2024
CONCLUSIONS: We found a negative relationship between higher CDAI scores and MAFLD. This study provided a new reference for exploring dietary interventions that affect MAFLD to reduce its incidence.
- Modern pharmacotherapy guidance for treating alcohol use disordersby Michael Soyka on December 20, 2024
INTRODUCTION: Alcohol use disorder (AUD) is prevalent and recognized as a chronic, relapsing disorder. Even though effective treatment options are available, AUD is strongly undertreated. As adjuvant treatment strategies accompanying psychosocial treatments, pharmacological strategies can increase the efficacy of AUD treatment options.
- Growth hormone secretagogue receptor and cannabinoid receptor type 1 intersection in the mouse brainby Camila Saenz on December 20, 2024
The growth hormone secretagogue receptor (GHSR) and the cannabinoid receptor type 1 (CB1R) are G-protein coupled receptors highly expressed in the brain and involved in critical regulatory processes, such as energy homeostasis, appetite control, reward, and stress responses. GHSR mediates the effects of both ghrelin and liver-expressed antimicrobial peptide 2, while CB1R is targeted by cannabinoids. Strikingly, both receptors mediate their effects by acting on common brain areas and their...