Truman Syndrome

The Truman Show delusion, informally known as Truman syndrome, is a type of delusion in which the person believes that their lives are staged reality shows, or that they are being watched on cameras.


Cluster Number:
Wiki Number: PW221
Diagnosis: Truman Syndrome
US Patients: several hundred cases, many after the “Truman Show” movie
World Patients:
Sex Ratio:
Age Onset:
Brain Area:
Symptoms: delusions, they believe their lives are staged reality shows being watched by cameras; in the past science fiction has people living in
Progression: worlds constructed by others, around one’s personal aspects
Causes: a variation on older delusinons of persecution or grandiosity


The world-wide medical research
reports chosen for each diagnosis 

Clicking each title opens the
PubMed article’s summary-abstract.

  • Home-Based Arm Cardiac Rehabilitation in Disabled Veterans: A Pilot Study
    by Anand Chockalingam on August 10, 2021

    One of the cornerstones of treatment after acute coronary syndromes is cardiac rehabilitation (CR). However, traditional CR remains underused in the United States due to comorbidities and geographical limitations. To evaluate feasibility and safety of our individually tailored CR program, we evaluated twelve weeks of tele-monitored home-based arm ergometer and weight training exercises in seven Veterans. Prior to beginning our CR program, all Veterans underwent an arm ergometer stress test and...

  • Discovery of Small Anti-ACE2 Peptides to Inhibit SARS-CoV-2 Infectivity
    by Pratik Adhikary on June 28, 2021

    COVID-19 is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which infects host cells by binding its viral spike protein receptor-binding domain (RBD) to the angiotensin converting enzyme 2 (ACE2) on host cells. Blocking the SARS-CoV-2-RBD/ACE2 interaction is, therefore, a potential strategy to inhibit viral infections. Using a novel biopanning strategy, a small anti-ACE2 peptide is discovered, which shows high affinity and specificity to human ACE2. It blocks not only...

  • Chronic subdural hemorrhage predisposes to development of cerebral venous thrombosis and associated retinal hemorrhages and subdural rebleeds in infants
    by Dale F Vaslow on June 25, 2021

    For infants presenting with subdural hemorrhage, retinal hemorrhage, and neurological decline the "consensus" opinion is that this constellation represents child abuse and that cerebral venous sinus thrombosis and cortical vein thrombosis is a false mimic. This article contends that this conclusion is false for a subset of infants with no evidence of spinal, external head, or body injury and is the result of a poor radiologic evidence base and misinterpreted data. Underdiagnosis of thrombosis is...

  • Altered ocular surface immune cell profile in patients with dry eye disease
    by Archana Padmanabhan Nair on April 16, 2021

    CONCLUSION: OS immune cell subset proportion changes in DED patients were associated with DED types and severity. The data suggests the potential for a new generation of therapies targeting immune cells on the ocular surface.