Substance-Related Disorder

A chronic disease characterized by uncontrolled drinking and preoccupation Excessive use of psychoactive drugs, such as alcohol, pain medications, or illegal drugs. It can lead to physical, social, or emotional harm.

 

Cluster Number:
Wiki Number: PW215
Diagnosis: Substance-Related Disorder
US Patients: 7% of adults; 5% for alcohol; 2% for other drugs; 72,000 deaths from drug overdoses in 2017; 88,000 alcohol&480,000 tobacco deaths
World Patients: 2017-271 million (5.5% of adults) have used illicit drugs and 35 million, have an use disorder; 585,000 drug-deaths
Sex Ratio: Alcohol-only disorder 237 million men and 46 million women; 3 million alcohol-related deaths.
Age Onset: Children have 2X substance use disorders if parents hae them vs. parents without them.
Brain Area:
Symptoms: persistent use despite harm and adverse consequences: alcohol, caffeine, pot, phencyclidine, hallucinogens, inhalants, opioids, etc
Progression: can be mild, moderate or severe damage
Causes:
Medications: detox; FDA has 2 for alcohol and opioid use; none for the cocaine, methamphetamine or other substance use disorders
Therapies:

Youtube Video: Substance Use Disorders-Dopamine Pathway

Youtube Video:

Substance Abuse Disorders

Amazon or Library Book:
Stahl’s Illustrated Substance Use and Impulsive Disorders

Support Group: Samhsa.gov; 800-662-4357

(U.S. Government Helpline)

Contact your local Social Security office for possible Disability Benefits through their Disability Determination Services,

Section 12.02.

4 CURRENT ARTICLES
FROM PUBMED

The world-wide medical research
reports chosen for each diagnosis 

Clicking each title opens the
PubMed article’s summary-abstract.

  • The Lancet Public Health Commission on gambling
    by Heather Wardle on November 4, 2024

    No abstract

  • Pallidal circuits drive addiction behavior
    by Rianne R Campbell on November 4, 2024

    Understanding the neural mechanisms that control addiction processes, including drug-seeking and relapse, is key to finding new targets for substance use disorder (SUD) pharmacotherapies and circuit-based therapies. Addictive drugs alter activity in distinct neural circuits that can lead to SUD symptoms, including compulsive drug craving and taking. This includes the pallidum, a region in the basal ganglia that acts as an integrator of associative, sensorimotor, and limbic information to shape...

  • Contingency Management for the Treatment of Substance Use Disorders: Enhancing Access, Quality, and Program Integrity for an Evidence-Based Intervention
    on November 4, 2024

    Expanding access to high-quality contingency management for the treatment of substance use disorder represents an important opportunity to accelerate efforts to address the overdose crisis, as well as the other substantial public health harms and costs related to untreated substance use disorders. This report to Congress, as required by Section 4127 of the Consolidated Appropriations Act, 2023, discusses opportunities and considerations for entities overseeing contingency management...

  • Mathematical modeling and analysis of the co-dynamics of crime and drug abuse
    by Dejen Ketema Mamo on November 3, 2024

    This study explores the dynamics of crime and substance abuse within a population by developing a novel mathematical model that integrates social interactions, rehabilitation efforts, and relapse probabilities. The model introduces a critical metric, the control reproduction number [Formula: see text], to quantify the invasion threshold for these behaviors. The findings reveal that the crime/substance-free equilibrium is globally asymptotically stable when [Formula: see text]. At the same time,...