Substance-Related Disorder
A chronic disease characterized by uncontrolled drinking and preoccupation Excessive use of psychoactive drugs, such as alcohol, pain medications, or illegal drugs. It can lead to physical, social, or emotional harm.
Cluster Number:
Wiki Number: PW215
Diagnosis: Substance-Related Disorder
US Patients: 7% of adults; 5% for alcohol; 2% for other drugs; 72,000 deaths from drug overdoses in 2017; 88,000 alcohol&480,000 tobacco deaths
World Patients: 2017-271 million (5.5% of adults) have used illicit drugs and 35 million, have an use disorder; 585,000 drug-deaths
Sex Ratio: Alcohol-only disorder 237 million men and 46 million women; 3 million alcohol-related deaths.
Age Onset: Children have 2X substance use disorders if parents hae them vs. parents without them.
Brain Area:
Symptoms: persistent use despite harm and adverse consequences: alcohol, caffeine, pot, phencyclidine, hallucinogens, inhalants, opioids, etc
Progression: can be mild, moderate or severe damage
Causes:
Medications: detox; FDA has 2 for alcohol and opioid use; none for the cocaine, methamphetamine or other substance use disorders
Therapies:
Youtube Video: Substance Use Disorders-Dopamine Pathway
Youtube Video:
Substance Abuse Disorders
Amazon or Library Book:
Stahl’s Illustrated Substance Use and Impulsive Disorders
Support Group: Samhsa.gov; 800-662-4357
(U.S. Government Helpline)
Contact your local Social Security office for possible Disability Benefits through their Disability Determination Services,
Section 12.02.
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Multiple material need insecurities and severity of psychological distress during the COVID-19 pandemic among women who use drugsby Catherine Tomko on December 20, 2024
CONCLUSIONS: WWUD experienced a substantial burden of multiple material needs during the pandemic which were associated with elevated levels of mental distress. Results speak to the need to advance mental health equity by addressing access to material needs and mental healthcare for marginalized populations, particularly during health emergencies that threaten already-precarious social safety nets and healthcare infrastructure.
- Harm reduction and its monitoring in Europe, from EMCDDA to EUDAby Alexis Goosdeel on December 20, 2024
CONCLUSION: Today's increasingly complex drug landscape, characterized by high substance availability, poly-drug use, and drug-related violence, necessitates a redefined approach to Harm Reduction. With the transformation of the EMCDDA into the European Union Drug Agency (EUDA), the agency's mandate now includes a proactive focus on anticipating, alerting, responding to, and learning from emerging drug-related challenges. Strengthening collaboration with civil society will be crucial in evolving...
- Modern pharmacotherapy guidance for treating alcohol use disordersby Michael Soyka on December 20, 2024
INTRODUCTION: Alcohol use disorder (AUD) is prevalent and recognized as a chronic, relapsing disorder. Even though effective treatment options are available, AUD is strongly undertreated. As adjuvant treatment strategies accompanying psychosocial treatments, pharmacological strategies can increase the efficacy of AUD treatment options.
- Neuroinflammatory history results in overlapping transcriptional signatures with heroin exposure in the nucleus accumbens and alters responsiveness to heroin in male ratsby Gabriele Floris on December 20, 2024
Recent progress in psychiatric research has highlighted neuroinflammation in the pathophysiology of opioid use disorder (OUD), suggesting that heightened immune responses in the brain may exacerbate opioid-related mechanisms. However, the molecular mechanisms resulting from neuroinflammation that impact opioid-induced behaviors and transcriptional pathways remain poorly understood. In this study, we have begun to address this critical knowledge gap by exploring the intersection between...