Sociopathy-Antisocial Personality Disorder

A mental health disorder characterized by disregard for other people.
Those with antisocial personality disorder (ASPD) may begin to show symptoms in childhood, but the condition can’t be diagnosed until adolescence or adulthood.
Those with antisocial personality disorder tend to lie, break laws, act impulsively, and lack regard for their own safety or the safety of others. Symptoms may lessen with age.
Treatment may include talk therapy and support for affected family members.


Cluster Number:
Wiki Number: PW209
Diagnosis: Sociopathy-Antisocial Personality Disorder
US Patients: 1.8% during a year
World Patients:
Sex Ratio: B3;G
Age Onset: age 10, before or after
Brain Area: high testosterone, low cortisol; lower serotonin, higher impulsiveness; less gray matter. Low prefrontal cortex acts
Symptoms: disregarding or violating others’ rights; exploit others with arrogance but no remorse;charming but impulsive ; con artists
Progression: frequently addicted; high crime rates with premeditated aggression; become dangerous burdens to families; aggressive in prisons
Causes: ADHD, oppositional defiant-disorder (ODD), genetic, birth-family environment, criminal and suicidal
Medications: no FDA approved medications for treatment; antipsychotics, antidepressants, mood stabilizers may reduce symptoms
Therapies: with little remorse, don’t typically cooperate with therapies, unless restrained by others


The world-wide medical research
reports chosen for each diagnosis 

Clicking each title opens the
PubMed article’s summary-abstract.

  • Childhood emotional abuse and motor impulsiveness among male violent inmates with antisocial personality disorder
    by Haocheng Chen on June 29, 2022

    This study aimed to explore the relationship among childhood maltreatment, impulsiveness and antisocial personality through a questionnaire survey of violent male inmates. We found that the scores of inmates with Antisocial Personality Disorder (ASPD) in Childhood Trauma Questionnaire-28 item Short Form (CTQ-SF) and Barratt Impulsive Scale-11 (BIS-11) were higher than those in the Non-Antisocial personality group, and there was a significant correlation between the scores of CTQ-SF and BIS-11....

  • Predictors of persistent alcohol use disorder and co-occurring depressive symptoms: Insights from the longitudinal college experiences study
    by Diana R Samek on June 27, 2022

    CONCLUSIONS: Findings suggest that personality factors, stress, and sleep in the first year of college may be useful targets to screen for in efforts to reduce long-term depressive symptoms in the college context. Disrupting affiliation with antisocial/substance-using peers and romantic partners and reducing the high quantity of alcohol and frequency of marijuana may be more relevant to reducing long-term problematic alcohol use. Implications for incorporating individually-tailored approaches to...

  • A study on methylation of two CpG islands of MAOA gene promoter among opium-addicted males undergoing methadone treatment
    by Vahid Omarmeli on June 27, 2022

    The association between methylation of MAOA gene promoter and alcohol and nicotine dependence has been demonstrated in women but not in men yet. Antisocial personality disorder (ASPD) and substance use disorders (SUD) are two types of disorders that could highly be influenced by methylation-induced changes in MAOA function. The aim of the current study is to investigate the effect of opioid addiction on methylation of MAOA gene promoter in males. DNA was extracted from the whole blood of all...

  • Differential Eating Behavior Patterns among the Dark Triad
    by Liping Shi on June 24, 2022

    There is little extant empirical literature examining the associations between Dark Triad (DT: Machiavellianism, narcissism, and psychopathy) and eating behaviors. The current study (n = 361) investigated the associations between Dark Triad and restrained eating, uncontrolled eating, and emotional eating in a sample drawn from the general population. The results from the study indicate that (a) despite expected sex differences in narcissism and primary psychopathy, no sex differences were found...