Insomnia is a common sleep disorder that, owing to difficulties falling asleep or maintaining sleep and/or early morning awakening, causes daytime functional impairment. Other sleep disorders include sleep-related breathing disorders; sleep-related movement disorders, such as periodic limb movement disorder and restless legs syndrome; parasomnias, such as rapid eye movement sleep behavior disorder and sleepwalking; and central disorders of hypersomnolence, such as narcolepsy. This article...

CONCLUSIONS: SRI is common in patients with iRBD and 18 % had pSRI despite intensive treatment, emphasizing the importance of bedside safety. The identification of risk factors for SRI and pSRI underscores the need for systematic clinical screening and targeted interventions for at-risk patients.

CONCLUSION: The majority of observed adverse reactions in this study were consistent with those listed in the product instructions. However, potential novel or notable ADE signals were identified through real-world pharmacovigilance analysis. It is anticipated that this paper will offer additional information regarding safe and rational medication for narcolepsy.

CONCLUSIONS: Our findings suggest that the arousal process is altered in DOA patients, and that specific EEG patterns are required for DOA episodes to emerge. These insights will help guide future research into the underlying circuits and objective markers of DOA.