The collective term sleep disorder refers to conditions that affect sleep quality, timing, or duration and impact a person’s ability to properly function while they are awake. These disorders can contribute to other medical problems, and some may also be symptoms for underlying mental health issues.
Wiki Number: PW204
Diagnosis: Sleep Disorder
Age Onset: children and adults
Brain Area: hippocampus-plaque increases lead to cell death
Symptoms: A “blanket term” for insomnia, apnea, narcolepsy, hypersomnia, sleepwalking, night terrors and sleeping sickness
Progression: sleep-disordered breathing, restless legs syndrome, bruxism-tooth grinding, sleep paralysis, shift-work
Causes: increased medication, changes in circadian rhythm, physiological problems, stress, traumatic brain injury, Alzheimer’s, allergies
Medications: for narcolepsy use modifinil
Therapies: hypnosis, music-inducing relaxation
The Rise of Sleep Disorders And What We Can Do About It
Amazon or Library Book: Sleep: How To Unleash Deep Sleep
Click the book to link or order from Amazon.
Support Group: sleepassociation.org; (American Sleep Association)
4 CURRENT ARTICLES
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- The risk of oral squamous cell carcinoma in patients with and without somatoform disorders including bruxism: A retrospective evaluation of 309,278 individualsby Marlene Heym on January 26, 2023
CONCLUSIONS: Psycho-emotional stress and/or chronic mucosal injuries may play a role in carcinogenesis. However, the results need to be interpreted cautiously due to limitations of the applied approach. It may thus far only be concluded that further research is necessary to investigate hypotheses regarding psychogenic carcinogenesis and tumor formation due to chronic tissue trauma.
- Nicotinamide Mononucleotide Ameliorates Sleep Deprivation-Induced Gut Microbiota Dysbiosis and Restores Colonization Resistance against Intestinal Infectionsby Dan Fang on January 26, 2023
Gut microbiota-mediated colonization resistance (CR) is crucial in protecting the host from intestinal infections. Sleep deprivation (SD) is an important contributor in the disturbances of intestinal homeostasis. However, whether and how SD affects host CR remains largely unknown. Here, it is shown that SD impairs intestinal CR in mice, whereas nicotinamide mononucleotide (NMN) supplementation restores it. Microbial diversity and metabolomic analyses suggest that gut microbiota and metabolite...
- Variability in oxidative stress-related genes (SOD2, CAT, GPX1, GSTP1, NOS3, NFE2L2, and UCP2) and susceptibility to migraine clinical phenotypes and featuresby Maria Papasavva on January 26, 2023
INTRODUCTION: Migraine is a complex disorder with genetic and environmental inputs. Cumulative evidence implicates oxidative stress (OS) in migraine pathophysiology while genetic variability may influence an individuals' oxidative/antioxidant capacity. Aim of the current study was to investigate the impact of eight common OS-related genetic variants [rs4880 (SOD2), rs1001179 (CAT), rs1050450 (GPX1), rs1695 (GSTP1), rs1138272 (GSTP1), rs1799983 (NOS3), rs6721961 (NFE2L2), rs660339 (UCP2)] in...
- Clinical-functional characteristics of children with asthma and obstructive sleep apnea overlap associated with attention deficit hyperactivity disorder: A cross-sectional studyby Le Nguyen-Ngoc-Quynh on January 26, 2023
CONCLUSION: The prevalence of OSA is increased among poorly controlled asthma. ADHD may have a higher prevalence in children with OSA. Therefore, prompt diagnosis of OSA will lead to an accurate asthma control strategy in patients with asthma.