Selective Mutism
Selective Mutism is a complex childhood anxiety disorder characterized by a child’s inability to speak and communicate effectively in select social settings, such as school. These children are able to speak and communicate in settings where they are comfortable, secure, and relaxed.
Cluster Number:
Wiki Number: PW200
Diagnosis: Selective Mutism
US Patients:
World Patients: .71 of 1% in 2002
Sex Ratio:
Age Onset: early childhood
Brain Area: amygdalas may become over-excited and this is a fight-flight response;
Symptoms: anxiety where people cannot speak in specific situations or places or to specific persons along with a social anxiety disorder.
Progression: Gets worse with age, contributing to depression, further anxiety and other social and emotional problems
Causes: some have experienced trauma; others, not
Medications: An SSRI, fluoxetine, has helped some children.
Therapies: Only change schools if the new one will be more supportive. Different techniques are described in the Wikipedia article.
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Delayed Toxic-Hypoxic Leukoencephalopathy As Sequela of Opioid Overdose and Cerebral Hypoxia-Ischemiaby David Chachkhiani on January 10, 2022
Delayed leukoencephalopathy in the aftermath of toxic exposure and cerebral hypoxia-ischemia is known as "delayed post-hypoxic leukoencephalopathy" (DPHL) but the name "delayed toxic-hypoxic leukoencephalopathy" (DTHL) may be more accurate if toxic and hypoxic mechanisms are both involved in the pathogenesis of delayed leukoencephalopathy. DTHL is characterized by initial recovery from toxic exposure and cerebral hypoxia-ischemia, clinical stability over a few weeks, and subsequent neurological...
- Sensory and motor electrophysiological mapping of the cerebellum in humansby Reiko Ashida on January 8, 2022
Cerebellar damage during posterior fossa surgery in children can lead to ataxia and risk of cerebellar mutism syndrome. Compartmentalisation of sensorimotor and cognitive functions within the cerebellum have been demonstrated in animal electrophysiology and human imaging studies. Electrophysiological monitoring was carried out under general anaesthesia to assess the limb sensorimotor representation within the human cerebellum for assessment of neurophysiological integrity to reduce the incidence...
- Cerebellar mutism syndrome in pediatric head trauma with cerebellar injuryby Anaïs Chivet on January 7, 2022
CONCLUSION: CMS after traumatic cerebellar injury does exist, even if it seems to be a very rare entity. It has to be better detected and studied in order to enrich pathophysiological knowledge about CMS of all etiologies and to bring our concerned patients the suitable follow-up and rehabilitative care that they could benefit from.
- Neoteric Approach of Fluoxetine Laden Orodispersible Film for Non-compliant Pediatric Patients of Selective Mutism and Obsessive-compulsive Disorderby Haseeb Anwar Dad on January 3, 2022
CONCLUSION: Fluoxetine ODFs of good pharmaceutical quality can be prepared on a small scale. Therefore, the perspective of using fluoxetine ODFs for individualized pharmacotherapy to ameliorate the compliance issues in selective mutism and OCD pediatric patients can be considered.