Seasonal Affective Disorder
Wiki Number: PW198
Diagnosis: Seasonal Affective Disorder
US Patients: 1.4% in Florida; 9.9% in Alaska
World Patients: Finland, 9.5%, Ireland, 20%
Brain Area: retinohypothalamic tract, suprachiasmatic nucleus, retina and pineal gland.
Symptoms: depressed in winter with over-sleeping, over-eating and too little energy, depressed thinking, loss of interest in activities
Causes: lack of available natural light
Medications: SSRI’s, Vitamin D, and othrs
Therapies: light therapy, melatonin, ionized air administration and CBT. Due to skin cancer threat, direct sunlight should be avoided. Eat fish.
4 CURRENT ARTICLES
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PubMed article’s summary-abstract.
- Elucidating treatment targets and mediators within a confirmatory efficacy trial: study protocol for a randomized controlled trial of cognitive-behavioral therapy vs. light therapy for winter depressionby Kelly J Rohan on May 13, 2022
BACKGROUND: This study is a confirmatory efficacy trial of two treatments for winter seasonal affective disorder (SAD): SAD-tailored group cognitive-behavioral therapy (CBT-SAD) and light therapy (LT). In our previous efficacy trial, post-treatment outcomes for CBT-SAD and LT were very similar, but CBT-SAD was associated with fewer depression recurrences two winters later than LT (27.3% in CBT-SAD vs. 45.6% in LT). CBT-SAD engaged and altered a specific mechanism of action, seasonal beliefs,...
- Biomolecular Assessment and Assay of Kisspeptin, Oxytocin and Melatonin in Female Depressed Patients on Antidepressant Therapy: A Comparative Studyby Ndudi K Oseyemwen on May 13, 2022
Depression, a common psychiatric disorder with a prevalence of 4.4%, a leading cause of disability and the fourth highest contributor to the global burden of diseases remains underdiagnosed. Biomarkers have been suggested to enable a better understanding of the variable responses to therapy observed in depression. Kisspeptin, oxytocin and melatonin have been implicated in the etiology of anxiety and neuropsychiatric disorders such as seasonal affective depression. This study aimed to compare the...
- Should clinicians and the general population be concerned about seasonal affective disorder in Australia?by Adriana G Nevarez Flores on May 7, 2022
- Blue-Light Therapy for Seasonal and Non-Seasonal Depression: A Systematic Review and Meta-Analysis of Randomized Controlled Trialsby André Do on May 6, 2022
CONCLUSIONS: The efficacy of blue-light therapy in the treatment of seasonal and non-seasonal MDD remains unproven. Future trials should be of longer duration, include larger sample sizes, and attempt to better standardize the parameters of light therapy.