Seasonal Affective Disorder
Wiki Number: PW198
Diagnosis: Seasonal Affective Disorder
US Patients: 1.4% in Florida; 9.9% in Alaska
World Patients: Finland, 9.5%, Ireland, 20%
Brain Area: retinohypothalamic tract, suprachiasmatic nucleus, retina and pineal gland.
Symptoms: depressed in winter with over-sleeping, over-eating and too little energy, depressed thinking, loss of interest in activities
Causes: lack of available natural light
Medications: SSRI’s, Vitamin D, and othrs
Therapies: light therapy, melatonin, ionized air administration and CBT. Due to skin cancer threat, direct sunlight should be avoided. Eat fish.
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4 CURRENT ARTICLES
The world-wide medical research
reports chosen for each diagnosis
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PubMed article’s summary-abstract.
- Verification, analytical validation and clinical validation (V3) of wearable dosimeters and light loggersby Manuel Spitschan on January 5, 2023
BACKGROUND: Light exposure is an important driver and modulator of human physiology, behavior and overall health, including the biological clock, sleep-wake cycles, mood and alertness. Light can also be used as a directed intervention, e.g., in the form of light therapy in seasonal affective disorder (SAD), jetlag prevention and treatment, or to treat circadian disorders. Recently, a system of quantities and units related to the physiological effects of light was standardized by the...
- Effect of MAOA DNA methylation on human in vivo protein expression measured by [ 11C]harmine positron emission tomographyby Patricia A Handschuh on December 27, 2022
CONCLUSIONS: In contrast to a previous study demonstrating an effect of methylation of a MAOA promoter region located further 5' on brain MAO-A, MAOA methylation of the region assessed here appears to affect brain protein levels to a limited extent at most. The observed effect of season on methylation levels is in accordance with extensive evidence for seasonal effects within the serotonergic system.
- Seasonality of hospitalization for schizophrenia and mood disorders: A single-center cross-sectional study in Chinaby Yitan Yao on November 27, 2022
CONCLUSIONS: We found that the seasonal distribution of psychiatric admissions was not uniform. And there was also an uneven seasonal distribution of length of stay for patients admitted in different seasons. This may imply that certain environmental factors that vary with the seasons are potential drivers of mental illness.
- Trait-Related Impulsivity, Affective Temperaments and Mood Disorders: Results from a Real-World Multicentric Studyby Mario Luciano on November 24, 2022
Trait-related impulsiveness is highly prevalent in patients with mood disorders, being associated with negative outcomes. The predictive role of affective temperaments on trait-related impulsivity is still understudied. The aim of the present study is to investigate the relationship between impulsivity and affective temperaments in a sample of euthymic patients with mood disorders. This is a real-world multicentric observational study, carried out at the outpatient units of seven university...