Catatonic schizophrenia, rare severe mental disorder characterized by striking motor behaviour, typically involving either significant reductions in voluntary movement or hyperactivity and agitation. In some cases, the patient may remain in a state of almost complete immobility, often assuming statuesque positions.
Diagnoses Schizophrenia (Out of aphpabetical order, but there is no entry for “Catatonic Schizophrenia.”)
WrldPatnts: 20 Mil
SexRatio: M1.5; F
AveOnset: Ages 16-30
Brain Area: insufficient dopamine to motivate; dopamine & glutamate; thinning of brain gyrus; being left handed
Symptoms: persecutory hallucinations (usually hearing), delusions (incorrect ideas), confused thinking; speaking in “word salad”
Progression & Effects: contact often lost with the outside world. 10% become violent = 4X general population
Causes: many genes and adverse childhood experiences; urban =2X; ½=drug use, including cannabis-2+X
Productive Medications: antipsychotics; social supports; 1/3 are “treatment resistant”, exercise, 3,000 new drugs in development
Productive Therapies: ½ improve over time, some with no relapses. Others, lifelong, frequent hospitalization, 5% suicides, 20 years shorter life
4 CURRENT ARTICLES
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PubMed article’s summary-abstract.
- Social behavior and spatial orientation in rat strains with genetic predisposition to catatonia (GC) and stereotypes (PM)by V S Plekanchuk on June 23, 2022
Various psychopathologies, including schizophrenia, bipolar disorder and major depression, are associated with abnormalities in social behavior and learning. One of the syndromes that may also take place in these disorders is catatonia. Catatonia is a psychomotor syndrome in which motor excitement, stereotypy, stuporous state, including the phenomenon of "waxy flexibility" (catalepsy), can be observed. Rats with genetic catatonia (GC) and pendulum-like movements (PM) of the anterior half of the...
- Remission of Persistent Negative Symptoms and Psychosocial Consequences by Combined Clozapine and Cariprazine Treatment in a Patient With Long-Standing Treatment-Resistant Schizoaffective Disorderby Mats Bogren on June 6, 2022
This patient case report describes a 45-year old white unmarried man with disability pension due to schizoaffective disorder, diagnosed at the age of 24. He lives in an apartment and has housing support. Retrospectively, the patient displayed prodromal markers of a disorder within the schizophrenia spectrum many years before the onset of frank psychosis, indeed since childhood. Over the years several symptoms and signs across schizophrenia domains have been manifest: positive, negative,...
- Efficacy of Transcranial Direct-Current Stimulation in Catatonia: A Review and Case Seriesby Alexandre Haroche on May 16, 2022
Catatonia is a severe neuropsychiatric syndrome, usually treated by benzodiazepines and electroconvulsive therapy. However, therapeutic alternatives are limited, which is particularly critical in situations of treatment resistance or when electroconvulsive therapy is not available. Transcranial direct-current stimulation (tDCS) is a promising non-invasive neuromodulatory technique that has shown efficacy in other psychiatric conditions. We present the largest case series of tDCS use in...
- A 45-year follow-up study of adolescent schizophrenia. Part II: Age of disease onset, type of onset of the disorder and presence of developmental burden in the context of disease course and long-term social functioning of patientsby Mariusz Ślosarczyk on May 15, 2022
CONCLUSIONS: The hidden type of onset of schizophrenia is the most important predictor of its later course.