Wiki Number: PW195
US Patients: 1.1% of the population;Life expectancy decreased by 20 years; sedentary life leads to heart attacks;
World Patients: 20 million total cases; 16.7 Million-disabled due to schizophrenia, 75% unemployed; Violence-6X population; with alcohol-24X.
Sex Ratio: M+;F
Age Onset: M-early 20’s; F-late 20’s and post-menopausal in women. Psychosis (reality-unreality) often preceeds schizophrenia.
Brain Area: dopamine controls positive motivations; genes CRHR1 and CRHBP relate to suicidal behavior, several brain areas involved
Symptoms: Hallucinations, delusions, disorganized thinking, withdrawal, apathy, weak emotions, word salad; cognitively poorer generally
Progression: Usually non-violent; more likely to be victims,unless using alcohol or drugs.
Causes: 70-80% heritable; raised in city, older parents, drugs or pot used as teenager, several factors during pregnancy; childhood traumas
Medications: antipsychotics, hospitalization to stop harm to self or others, many create restlessness, muscle-jerking, weight gain
Therapies: exercise, CBTs, other talking therapies, along with medications, ½improve, some get well; the other half, life-time involvement.
Youtube Video: How Paranoid Schizophrenia Impacts My Life
Youtube Video: What is Schizophrenia?
Amazon or Library Book: Surviving Schizophrenia
Click the book to link or order from Amazon.
Support Group: sczaction.org 1-800-493-2094
(Schizophrenia Action Alliance)
Contact your local Social Security office for possible Disability Benefits under their Disability Determination Services,
4 CURRENT ARTICLES
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- The different trends in the burden of neurological and mental disorders following dietary transition in China, the USA, and the world: An extension analysis for the Global Burden of Disease Study 2019by Shan Liang on January 26, 2023
INTRODUCTION: The highly processed western diet is substituting the low-processed traditional diet in the last decades globally. Increasing research found that a diet with poor quality such as western diet disrupts gut microbiota and increases the susceptibility to various neurological and mental disorders, while a balanced diet regulates gut microbiota and prevents and alleviates the neurological and mental disorders. Yet, there is limited research on the association between the disease burden...
- Understanding FABP7 binding to fatty acid micelles and membranesby Stefan Lenz on January 26, 2023
Fatty acid binding proteins (FABPs) are chaperones that facilitate the transport of long-chain fatty acids within the cell and can provide cargo-dependent localization to specific cellular compartments. Understanding the nature of this transport is important because lipid signaling functions are associated with metabolic pathways impacting disease pathologies including cancer, autism, and schizophrenia. FABPs often associate with cell membranes to acquire and deliver their bound cargo as part of...
- Markers of muscarinic deficit for individualized treatment in schizophreniaby Heiner Stuke on January 26, 2023
Recent clinical studies have shown that agonists at muscarinic acetylcholine receptors effectively reduce schizophrenia symptoms. It is thus conceivable that, for the first time, a second substance class of procholinergic antipsychotics could become established alongside the usual antidopaminergic antipsychotics. In addition, various basic science studies suggest that there may be a subgroup of schizophrenia in which hypofunction of muscarinic acetylcholine receptors is of etiological...
- Changes in major psychiatric disorders in children and adolescents from 2001 to 2020: A retrospective single-center studyby Hongyu Zheng on January 26, 2023
CONCLUSION: Although there is a significant downward trend in the percentage of hospitalizations for SCZ, it is still the most common psychiatric disorder in children and adolescents. We observed a significant increase in the percentage of hospitalizations for DD and CED. In addition, the proportion of female patients being hospitalized is on the rise, and this aspect requires continuous attention.