Schizoid Personality Disorder

A condition in which people avoid social activities and interacting with others.
Schizoid personality disorder typically begins in early adulthood.
People with this condition don’t desire or enjoy close relationships, even with family, and are often seen as loners. They may be emotionally cold and detached.
Therapy and medications, such as antidepressants or mood stabilizers, can help.


Cluster Number:
Wiki Number: PW194
Diagnosis: Schizoid Personality Disorder
US Patients: 1-4% (unclear if that is of the general or psychiatric patient %), poorly studied, because few with the problem seek treatment.
World Patients:
Sex Ratio: M+;F
Age Onset:
Brain Area:
Symptoms: uninterested in social relationships, detachment, apathy; a rich internal fantasy world. Feels like an “observer” in life, asexual.
Progression: The are commonly bullied; often consider suicide but few attempt it. Little self-disclosure or social intimacy. Creative thinkers.
Causes: Is preoccupied with inner experience; does not desire “limiting” social relationships. perfectionistic, 50% heritable.
Medications: antipsychotics to alleviate social defects and blunted affect, part of the schizophrenic spectrum; bupriopion
Therapies: Helping them learn about their emotions-if they want to to develop commonalities and feel and be more “connected” with others


The world-wide medical research
reports chosen for each diagnosis 

Clicking each title opens the
PubMed article’s summary-abstract.

  • Functional MRI findings in personality disorders: A review
    by Oskar Zarnowski on September 1, 2021

    Personality disorders (PDs) have a prevalence of approximately 10% in the United States, translating to over 30 million people affected in just one country. The true prevalence of these disorders may be even higher, as the paucity of objective diagnostic criteria could be leading to underdiagnosis. Because little is known about the underlying neuropathologies of these disorders, patients are diagnosed using subjective criteria and treated nonspecifically. To better understand the neural...

  • First depressive episode in the dynamics of personality disorders in adolescence
    by E S Krylova on August 18, 2021

    CONCLUSIONS: The revealed clinical and psychopathological features will contribute to the creation of a unified model for predicting affective disorders and the formation of therapy standards.

  • Autistic Personality Traits and Treatment Outcome for Alcohol Use Disorders
    by Malin Hildebrand Karlén on May 9, 2021

    The importance of personality traits for the outcome of psychiatric treatment, including treatment for alcohol use disorder (AUD), has been widely acknowledged. Also, research on autism spectrum disorders has evolved in recent years, emphasizing that the behavioral traits within these neuropsychiatric disorders exist on a dimension both within and outside the boundaries of psychopathology. In the present study, the relationship between personality traits associated with autistic functioning and...

  • A third hierarchical level of narrower traits for the Dimensional Assessment of Personality Pathology-Basic Questionnaire
    by Fernando Gutiérrez on April 19, 2021

    Current dimensional taxonomies of personality disorder show a stronger empirical grounding than categories, but may lack the necessary level of detail to make accurate predictions and case formulations. We need to further develop the lower levels of the hierarchy until reaching the building blocks of personality pathology. The Dimensional Assessment of Personality Pathology-Basic Questionnaire (DAPP-BQ) is well-suited to this purpose due to its multilayered structure and its agreement with the...