Schizoid Personality Disorder

A condition in which people avoid social activities and interacting with others.
Schizoid personality disorder typically begins in early adulthood.
People with this condition don’t desire or enjoy close relationships, even with family, and are often seen as loners. They may be emotionally cold and detached.
Therapy and medications, such as antidepressants or mood stabilizers, can help.


Cluster Number:
Wiki Number: PW194
Diagnosis: Schizoid Personality Disorder
US Patients: 1-4% (unclear if that is of the general or psychiatric patient %), poorly studied, because few with the problem seek treatment.
World Patients:
Sex Ratio: M+;F
Age Onset:
Brain Area:
Symptoms: uninterested in social relationships, detachment, apathy; a rich internal fantasy world. Feels like an “observer” in life, asexual.
Progression: The are commonly bullied; often consider suicide but few attempt it. Little self-disclosure or social intimacy. Creative thinkers.
Causes: Is preoccupied with inner experience; does not desire “limiting” social relationships. perfectionistic, 50% heritable.
Medications: antipsychotics to alleviate social defects and blunted affect, part of the schizophrenic spectrum; bupriopion
Therapies: Helping them learn about their emotions-if they want to to develop commonalities and feel and be more “connected” with others


The world-wide medical research
reports chosen for each diagnosis 

Clicking each title opens the
PubMed article’s summary-abstract.

  • Personality Disorder
    by Kamron A. Fariba on January 1, 2022

    Temperament classification dates back as far as ancient Greece when Hippocrates proposed his humoral theory regarding the classifications of behavior. The postulated temperaments, consisting of sanguine, choleric, melancholic, and phlegmatic, remained in use as recently as the 20th century. Emil Kraepelin classified manic-depressive patients as depressive, hypomanic, or irritable, which in turn correlated with melancholic, sanguine, or choleric dispositions, respectively. These, in turn, evolved...

  • Schizoid Personality Disorder
    by Kamron A. Fariba on January 1, 2022

    In the 5th century B.C., Hippocrates first propounded his theory of humorism to describe the different temperaments. This idea postulated that human behavior could be categorized into four distinct temperaments, black bile, sanguine (blood), yellow bile, and phlegm, which in turn correlated with the four elements earth, air, fire, and water, respectively. Hippocrates further elaborated on his theory by describing black bile as melancholic, sanguine as optimistic, yellow bile as irritable and...

  • Avoidant Personality Disorder
    by Kamron A. Fariba on January 1, 2022

    In the 5th century B.C., Hippocrates offered his hypothesis regarding the origin of behavior with his humoral theory, postulating temperament was derived from the heterogeneous balance of the four distinct humors in the body. The four humors consisted of black bile - melancholic, yellow bile - irritable, phlegm - apathetic, and blood - sanguine. The humors and their subsequent temperaments supposedly embodied the elements of earth, fire, water, and air, respectively. References to this nascent...

  • Family History of Psychiatric Disorders and Clinical Factors Associated With a Schizophrenia Diagnosis
    by Lina Díaz-Castro on November 30, 2021

    CONCLUSION: Male gender, showing premorbid schizoid-like personality, familial SCH, and obstetric trauma are risk factors that distinguish SCH from BD. Additionally, our results suggest that risk for SCH relative to BD may be importantly influenced by interactions between familial risk, gender, and obstetric trauma.