Schizoaffective Disorder
Cluster Number:
Wiki Number: PW193
Diagnosis: Schizoaffective Disorder-Much of the Wikipedia article dealt with the validity of this particular diagnosis.
US Patients: 0.5-.0.8 (less than 1)% sometime in their lives
World Patients:
Sex Ratio: M;W+. More women in depressive; about even numbers in bipolar areas.
Age Onset: 30% between ages 25 and 35.
Brain Area: abnormal thoughts, unstable mood; psychotic symptoms for two weeks without any mood disorders. IT’s often misdiagnosed.
Symptoms: Bipolar has mania; hypomania and mixed episode vs. depressive only. May have hallucinations, delusions, disorganized speech and
Progression: thinking. May include audiotory hasllucinations.
Causes: Genetics under environmental stresses; age of the father at conception; pot and other substance abuses may be factors as well.
Medications: antipsychotics, mood stabilizers and antidepressants; electroconvulsive therapy for severe and resistant symptoms.
Therapies: Returning the patient to do the normal activities of life along with vocational rehabilitation.
Youtube Video:
Schizophrenia vs. Schizophreniform vs. Schizoid vs. Schizotypal
Amazon or Library Book: Schizoaffective Disorder
Click the book to link or order from Amazon.
Contact your local Social Security office for possible Disability Benefits through their Disability Determination Services,
Section 12.03.
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Clozapine Efficacy and Adverse Drug Reactions Among a Nationwide Study of 1021 Australians Prescribed Clozapine: The ClozaGene Studyby Penelope A Lind on May 7, 2024
CONCLUSIONS: Our findings highlight the high rate of psychotic and metabolic symptoms and ADRs among adults prescribed clozapine in the general Australian population. Future genomic analyses will focus on identifying genetic variants influencing clozapine treatment response and side effects.
- Sex Differences Between Female and Male Individuals in Antipsychotic Efficacy and Adverse Effects in the Treatment of Schizophreniaby Megan Galbally on May 7, 2024
CONCLUSIONS: While overall sex differences were limited across efficacy and tolerability for antipsychotic treatment, there were some specific findings with risperidone. Further examination of sex differences within antipsychotic trials will be important to improve efficacy and reduce adverse responses across as well as individualising care for people with schizophrenia.
- Faster bi-stable visual switching in psychosisby Kyle W Killebrew on May 7, 2024
Bi-stable stimuli evoke two distinct perceptual interpretations that alternate and compete for dominance. Bi-stable perception is thought to be driven at least in part by mutual suppression between distinct neural populations that represent each percept. Abnormal visual perception has been observed among people with psychotic psychopathology (PwPP), and there is evidence to suggest that these visual deficits may depend on impaired neural suppression in the visual cortex. However, it is not yet...
- Treadmill exercise training inhibits morphine CPP by reversing morphine effects on GABA neurotransmission in D2-MSNs of the accumbens-pallidal pathway in male miceby Yi-Gang Dong on May 7, 2024
Relapse is a major challenge in the treatment of drug addiction, and exercise has been shown to decrease relapse to drug seeking in animal models. However, the neural circuitry mechanisms by which exercise inhibits morphine relapse remain unclear. In this study, we report that 4-week treadmill training prevented morphine conditioned place preference (CPP) expression during abstinence by acting through the nucleus accumbens (NAc)-ventral pallidum (VP) pathway. We found that neuronal excitability...