Schizoaffective Disorder

Schizoaffective disorder is a combination of symptoms of schizophrenia and mood disorder, such as depression or bipolar disorder. Symptoms may occur at the same time or at different times.
Cycles of severe symptoms are often followed by periods of improvement. Symptoms may include delusions, hallucinations, depressed episodes, and manic periods of high energy.
People with this disorder generally do best with a combination of medications and counseling.


Cluster Number:
Wiki Number: PW193
Diagnosis: Schizoaffective Disorder-Much of the Wikipedia article dealt with the validity of this particular diagnosis.
US Patients: 0.5-.0.8 (less than 1)% sometime in their lives
World Patients:
Sex Ratio: M;W+. More women in depressive; about even numbers in bipolar areas.
Age Onset: 30% between ages 25 and 35.
Brain Area: abnormal thoughts, unstable mood; psychotic symptoms for two weeks without any mood disorders. IT’s often misdiagnosed.
Symptoms: Bipolar has mania; hypomania and mixed episode vs. depressive only. May have hallucinations, delusions, disorganized speech and
Progression: thinking. May include audiotory hasllucinations.
Causes: Genetics under environmental stresses; age of the father at conception; pot and other substance abuses may be factors as well.
Medications: antipsychotics, mood stabilizers and antidepressants; electroconvulsive therapy for severe and resistant symptoms.
Therapies: Returning the patient to do the normal activities of life along with vocational rehabilitation.

Youtube Video:

Schizophrenia vs. Schizophreniform vs. Schizoid vs. Schizotypal

Amazon or Library Book: Schizoaffective Disorder

Contact your local Social Security office for possible Disability Income Benefits under their categpry 12.03.


The world-wide medical research
reports chosen for each diagnosis 

Clicking each title opens the
PubMed article’s summary-abstract.

  • Hippocampal structural alterations in early-stage psychosis: Specificity and relationship to clinical outcomes
    by Gina Brunner on July 3, 2022

    Hippocampal dysfunctions are a core feature of schizophrenia, but conflicting evidence exists whether volumetric and morphological changes are present in early-stage psychosis and to what extent these deficits are related to clinical trajectories. In this study, we recruited individuals at clinical high risk for psychosis (CHR-P) (n = 108), patients with a first episode of psychosis (FEP) (n = 37), healthy controls (HC) (n = 70) as well as a psychiatric control group with substance abuse and...

  • Medical genetics in the 19th century as background to the development of psychiatric genetics
    by Kenneth S Kendler on July 2, 2022

    This article examines the relationship between the early efforts of alienists to understand the role of heredity in the etiology of insanity in the 19th century and the parallel efforts of the nascent discipline of medical genetics. I review three monographs on general medical genetics: Adams in 1814, Steinau in 1843, and Lithgow in 1889. Numerous parallels were seen between their writings and those of their contemporary alienists working on mental disorders including (i) an emphasis on the...

  • Stakeholder views on mindfulness for youth at risk for psychosis
    by Daniel Reich on July 2, 2022

    Interventions incorporating mindfulness for youth identified to be at risk for psychosis show promise for symptom management yet to be addressed by other approaches. Important questions remain as to how to safely and effectively implement these interventions with this cohort. The aim of this research was to collaboratively identify with stakeholders of such interventions, namely youth at risk for psychosis, and practitioners with experience working with youth at risk for psychosis - attitudes...

  • Four-repeat tauopathies and late-onset psychiatric disorders: Etiological relevance or incidental findings?
    by Osamu Yokota on July 1, 2022

    Argyrophilic grain disease (AGD), progressive supranuclear palsy (PSP) and corticobasal degeneration are four-repeat (4R) tauopathies that develop in the presenium or later. Whether these diseases are associated with the occurrence of late-onset psychiatric disorders remains unclear. To facilitate the accumulation of clinicopathological findings regarding this issue, we here present a selected series of 11 cases that clinically developed psychotic disorder (n = 7; age at onset: 41-75 years),...