Premenstrual Dysphoric Disorder

A severe, sometimes disabling extension of premenstrual syndrome.

Premenstrual dysphoric disorder (PMDD) is a severe form of premenstrual syndrome that includes physical and behavioral symptoms that usually resolve with the onset of menstruation.

PMDD causes extreme mood shifts that can disrupt work and damage relationships. Symptoms include extreme sadness, hopelessness, irritability, or anger, plus common premenstrual syndrome symptoms such as breast tenderness and bloating.

Drugs and lifestyle changes may help.

Cluster Number:
Wiki Number: PW175
Diagnosis: Premenstrual Dypshoric Disorder
US Patients:
World Patients: 1.8-5.8% of menstruating women.
Sex Ratio:
Age Onset:
Brain Area: serotonin receptors in the hippocampus and prefrontal cortex are affected by estrogen and progesterone activities
Symptoms: pain and mood changes for up to two weeks before menstruation.
Progression:
Causes: genetic and fluctuating hormones during the menstrual cycle;
Medications: antidepressants, SSRIs, ovulation suppression with birth-control pills and GnRH analogues. SSRIs are most common & help 50%.
Therapies: CBT

CLICK HERE FOR THE FULL WIKIPEDIA ARTICLE

Youtube Video:

What It’s Like To Have Premenstrual Dysphoric Disorder

Amazon or Library Book: The PMDD Phenomenon

Click the book to link or order from Amazon.

Support Group” viciouscyclepmdd.com-iampt.org

(International Association for Premenstrual Disorder)

4 CURRENT ARTICLES
FROM PUBMED

The world-wide medical research
reports chosen for each diagnosis

Clicking each title opens the
PubMed article’s summary-abstract.

Association between adverse childhood experiences and menstruation-related symptoms among Japanese female workers: A cross-sectional study
by Yoshiaki Kanamori on January 19, 2025
CONCLUSIONS: Expanded ACEs were associated with menstruation-related symptoms. The results suggested the importance of trauma-informed care in gynecology, obstetrics, and occupational health practice.
Overlooked consequences of undiagnosed Premenstrual Dysphoric Disorder in Pakistani women
by Hania Waseem on January 19, 2025
No abstract
Improving care experiences for premenstrual symptoms and disorders in the United Kingdom (UK): a mixed-methods approach
by E L Funnell on January 13, 2025
CONCLUSIONS: Poor care experiences for premenstrual symptoms in the UK are characterised by dismissive attitudes and perceived lack of knowledge. Improved training provision for healthcare professionals is required to address this and other aspects of care identified by qualitative analysis. However, research is needed to identify appropriate methods to deliver training. Utilisation of standardised screening tools and patient-centred communication will likely ensure comprehensive assessments and...
Psychological stress dysfunction in women with premenstrual syndrome
by Qing Liu on January 3, 2025
Premenstrual syndrome (PMS) encompasses a range of emotional, physiological, and behavioral symptoms that occur during the luteal phase of the menstrual cycle (MC) and resolve with the onset of menstruation. These symptoms, which can include fatigue, physical pain, anxiety, irritability, and depression, significantly affect women's daily lives and overall well-being. In severe cases, PMS can progress to premenstrual dysphoric disorder (PMDD), profoundly impairing quality of life. Despite its...