Premature Ejaculation
Premature ejaculation (PE) is when you have an orgasm before intercourse or less than a minute after you start. There is no set time when a man should ejaculate during sex, but if you ejaculate and lose your erection this soon, you and your partner may feel there’s not enough time to enjoy it.
Cluster Number:
Wiki Number: PW174
Diagnosis: Premature Ejaculation
US Patients: 4-8 minutes is typical ejaculation.
World Patients:
Sex Ratio:
Age Onset:
Brain Area:
Symptoms: Male has orgasm and expels semen with minimal penile stimulation.
Progression:
Causes:
Medications: SSRIs slowed the process, but had negative side effects later.
Therapies: Stopping movement before ejaculation helped 50% of couples in studies.
Youtube Video: Urologist explains Premature Ejaculation
Amazon or Library Book: Pemature Ejaculation
Click the book to link or order from Amazon.
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- A New and Safe Delivery of Sildenafil Citrate Co-Evaporate Loaded Emulgels for the Cure of Certain Male Sexual Dysfunctionsby Shaaban K Osman on January 17, 2025
The present work focuses on the production of sildenafil co-evaporates loaded emulgels as topical dosage forms for the treatment of premature ejaculation and erectile dysfunction. Topical administration of sildenafil citrate (SILD) co-evaporates is expected to improve the bioavailability profile of the drug and to avoid the severe side effects accompanying the traditional SILD dosage forms, especially for prohibited cardiovascular cases. Firstly, the solubility of SILD was improved via solid...
- Development and in vitro/in vivo evaluation of taste-masked orodispersible films of dapoxetine hydrochloride using ion exchange resinsby Ying Zhou on January 17, 2025
Dapoxetine hydrochloride tablets are the most commonly used drug for the treatment of premature ejaculation (PE). However, the tablets must be taken with water 1-3 h before sexual activity, which makes the medication intake conspicuous and inconvenient. This study aimed to develop taste-masked orodispersible films (ODFs) of dapoxetine hydrochloride using ion exchange resins. It was found that the based-Kyron T-134 resin complex achieved a high drug loading of 75.9 ± 1.4%, establishing the mass...
- From spermatogenesis to fertilisation: the role of melatonin on ram spermatozoaby Adriana Casao on January 17, 2025
This review presents recent findings on the effect of melatonin on ram spermatozoa. This hormone regulates seasonal reproduction in the ovine species through the hypothalamic-pituitary-gonadal axis, but it also exerts direct effects on spermatogenesis, seminal quality and fertility. In the testis, melatonin stimulates blood flow to this organ, but it also appears to be involved in the differentiation of spermatogonial stem cells and the secretion of testosterone through the MT1 and MT2...
- The value of 5-HT, leptin, and NE in the classification of premature ejaculationby Zhimin Chen on January 14, 2025
CONCLUSION: The serum 5-HT, leptin, and NE levels in PE patients may contribute to the classification of PE.