Post Traumatic Stress Disorder
Wiki Number: PW173
Diagnosis: Posttraumatic Stress Disorder
US Patients: 3.5% in a given year; 3.9% over a life-time;
World Patients: Much higher where wars have occurred.
Sex Ratio: M;W+. After rape, about 19% develop PTSD
Age Onset: less likel to develop PTSD if traumatic event occurs before age 10;
Brain Area: women with smaller hippocampi; more norepinephrine; brain shrinkage, but hyperactive amygdala.
Symptoms: after a traumatic event, thoughts, dreams, mental or physical distress, changes in thought, increased fight-flight, self-harm, suicide
Progression: intrusive, recurrent recollections, flashbacks, and nightmares; depression, anxiety and mood disordersl drug or alcohol abuse
Causes: previous rape or child abuse; war, refugee status; death of a loved one; cancer, heart attack, stroke;child in chronic illness’s parents
Medications: antidepresssants and SSRI’s help 50%;
Therapies: Eye Movement Desensitization and Reprocessing helped 50% in children and adolescents.
Youtube Video: 3 Ways to Manage PTSD Triggers
Amazon or Library Book: Post-Traumatic Stress Disorder Workbook
Click the book to link or order from Amazon.
Support Group: samhsa.gov; 800-662-4357
(U.S. Substance Abuse and Mental Health Services Administration)
Contact your local Social Security office for possible Disability Benefits through their Disability Determination Services,
4 CURRENT ARTICLES
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Sex-dependent effects of microglial reduction on impaired fear extinction induced by single prolonged stressby Orlando Torres-Rodriguez on January 26, 2023
Single prolonged stress (SPS) is a preclinical rodent model for studying post-traumatic stress disorder (PTSD)-like behaviors. Previously we found that increased expression of the microglial marker Iba-1 in the ventral hippocampus after SPS exposure was associated with impaired fear extinction, suggesting that microglial activity contributed to the SPS-induced behavioral changes. To test this, we examined whether reducing microglia with the colony-stimulating factor 1 receptor blocker, PLX3397,...
- Dissociation, trauma and the experience of visual hallucinations in post-traumatic stress disorder and schizophreniaby Yann Quidé on January 26, 2023
Dissociative behaviours and hallucinations are often reported in trauma-exposed people with schizophrenia spectrum disorders and post-traumatic stress disorder (PTSD). Auditory hallucinations are the most commonly reported type of hallucination, but often co-occur with experiences in other sensory modalities. The phenomenology and the neurobiological systems involved in visual experiences are not well characterised. Are these experiences similar in nature, content or severity among people with...
- Early self-reported post-traumatic stress symptoms after trauma exposure and associations with diagnosis of post-traumatic stress disorder at 3 months: latent profile analysisby Chia-Hao Shih on January 26, 2023
CONCLUSIONS: These findings fill the knowledge gap of identifying possible subgroups of individuals based on their PTSS severity during the early post-trauma period and investigating the relationship between subgroup membership and PTSD development, which have important implications for clinical practice.
- Quetiapine Treatment for Post-traumatic Stress Disorder: A Systematic Review of the Literatureby Calogero Crapanzano on January 26, 2023
Paroxetine and Sertraline are the only medications approved in posttraumatic stress disorder (PTSD). However, about 60% of traumatized patients fail to show an adequate clinical response. Second generation antipsychotics are recommended as second-line monotherapy or third-line augmentation strategies and quetiapine appears as one of the most used and promising agents. Up to date, no reviews assessed the efficacy of quetiapine in the treatment of PTSD. We aimed to assess the effectiveness and...