Post Traumatic Stress Disorder
Cluster Number:
Wiki Number: PW173
Diagnosis: Posttraumatic Stress Disorder
US Patients: 3.5% in a given year; 3.9% over a life-time;
World Patients: Much higher where wars have occurred.
Sex Ratio: M;W+. After rape, about 19% develop PTSD
Age Onset: less likel to develop PTSD if traumatic event occurs before age 10;
Brain Area: women with smaller hippocampi; more norepinephrine; brain shrinkage, but hyperactive amygdala.
Symptoms: after a traumatic event, thoughts, dreams, mental or physical distress, changes in thought, increased fight-flight, self-harm, suicide
Progression: intrusive, recurrent recollections, flashbacks, and nightmares; depression, anxiety and mood disordersl drug or alcohol abuse
Causes: previous rape or child abuse; war, refugee status; death of a loved one; cancer, heart attack, stroke;child in chronic illness’s parents
Medications: antidepresssants and SSRI’s help 50%;
Therapies: Eye Movement Desensitization and Reprocessing helped 50% in children and adolescents.
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- False memory in posttraumatic stress disorder and borderline personality disorderby Annemarie Miano on July 2, 2022
Post-traumatic stress disorder (PTSD) and borderline personality disorder (BPD) have been associated with an increased generation of false memories. We aimed to disentangle disorder-specific false memory in individuals with PTSD and BPD using the Deese-Roediger-McDermott (DRM) paradigm. It measures the tendency to mistakenly remember stimuli that are associated with actually presented material, but have not been presented. Participants with BPD without comorbid PTSD (n = 32), participants with...
- BDNF Val66Met genotype and adolescent glucocorticoid treatment induce sex-specific disruptions to fear extinction and amygdala GABAergic interneuron expression in miceby Sharvada Raju on July 2, 2022
CONCLUSION: BDNF Val66Met genotype interacts with chronic adolescent stress hormone exposure to abolish fear extinction in female Met/Met mice in adulthood. This effect was associated with female-specific interneuron dysfunction induced by either genotype or stress hormone exposure, depending on the interneuron subtype. These data provide biological insight into the role of BDNF in sex differences in sensitivity to stress and vulnerability to stress-related disorders in adulthood.
- Moral Injury and Recovery in Uniformed Professionals: Lessons From Conversations Among International Students and Expertsby Jonathan Jin on July 1, 2022
CONCLUSION: Exposure to PMIEs can have devastating impacts on military members, leaders and other uniformed professionals. This may lead to development of MI and PTSD. Recognizing MI as honorable may reduce stigma and psychological harm, and facilitate help-seeking among uniformed personnel and other trauma-affected populations. Salient efforts to address MI must include use of accurate measurements of MI and integrated holistic therapeutic approaches, inclusive of spiritual and social...
- Sensorimotor Interaction Against Traumaby Giada Persichilli on July 1, 2022
No abstract