Paranoid Personality Disorder

Paranoid personality disorder (PPD) is one of a group of conditions called “Cluster A” personality disorders which involve odd or eccentric ways of thinking. People with PPD also suffer from paranoia, an unrelenting mistrust and suspicion of others, even when there is no reason to be suspicious.


Cluster Number:
Wiki Number: PW151
Diagnosis: Paranoid Personality Disorder
US Patients: .5%-2.5% of the general population
World Patients:
Sex Ratio: M+;F
Age Onset:
Brain Area:
Symptoms: paranoid delusions, mistrust of others, constantly seeking validation of their fears and mistrust. Isolate themselves.
Progression: suspicious, preoccupied with friends’ loyalty, bears grudges, quick to attack and counterattack, fears spousal infidelity
Causes: heritable, overvalue their capabilities and attribute limitations or failures to the deviancy of others
Medications: antidepressants, antipsychotics and anti-anxiety medications

Youtube Video: The Mistrust of Paranoid Personality

Amazon or Library Book: Understanding Paranoia

Support Group: (National Alliance on Mental Illness)


The world-wide medical research
reports chosen for each diagnosis 

Clicking each title opens the
PubMed article’s summary-abstract.

  • A Case Report of Leukocytosis During Modified Electroconvulsive Therapy of Paranoid Personality Disorder
    by Xingyu Mu on June 13, 2022

    CONCLUSION: Before MECT, it is necessary to screen blood cytology. During and after MECT, we should be alert to leukocytosis that may be related to MECT and deal with it correctly in time.

  • Comorbid bipolar disorder and borderline personality disorder: Diagnosis using machine learning
    by Adam Bayes on June 13, 2022

    Comorbid bipolar disorder (BP) and borderline personality disorder (BPD) presents a diagnostic challenge in its differentiation from each condition individually. We aimed to use a machine learning (ML) approach to differentiate comorbid BP/BPD from both BP and BPD. Participants were assigned DSM diagnoses and compared on self-report measures examining personality, emotion regulation strategies and perceived parental experiences during childhood. 82 participants were assigned as BP, 52 as BPD and...

  • Predictors of personality disorders in prisoners
    by Fayegh Yousefi on June 1, 2022

    Personality disorders can lead to difficult social or occupational functional processes rooted in chronic maladaptive thoughts, feelings, and behaviors. This study aimed to investigate factors of personality disorder in prisoners from the central prison of Sanandaj, Iran. We conducted a cross-sectional study, which included all prisoners in the central prison of Sanandaj, Iran. The study sample includes 343 prisoners, of which 329 were male, and 14 were female, selected by randomized multistage...

  • Prevalence of Personality Disorders Across Veteran Samples: A Meta-Analysis
    by Emily R Edwards on June 1, 2022

    Despite priorities around mental health, Veteran health care organizations have historically considered personality disorders to be preexisting conditions ineligible for disability benefits. However, growing evidence suggests potentially elevated prevalence of these disorders among military and Veteran samples and attests to implications of risk. The current study provides a meta-analytic review of literature on the prevalence of personality disorders in Veteran samples. Analysis of 27 unique...