Nicotine Dependence
Nicotine dependence is a state of dependence upon nicotine. Nicotine dependence is a chronic, relapsing disease defined as a compulsive craving to use the drug, despite social consequences, loss of control over drug intake, and emergence of withdrawal symptoms. Tolerance is another component of drug dependence.
Cluster Number:
Wiki Number: PW133
Diagnosis: Nicotine Dependence
US Patients:
World Patients: 976 Million Smokers
Sex Ratio:
Age Onset:
Brain Area: Nicotine stimulates receptors in the adrenal medulla and throughout the central and peripheral nervous systems.
Symptoms: Nicotine stimulates brain areas affecting reward, pleasure and anxiety and induce cravings when not involved.
Progression:
Causes: Several genes are involved in dependency; compulsive craving for nicotine despite knowing consequences;
Medications: There are drugs and patches to reduce responsiveness to nicotine.
Therapies: Evidence-Based Medicine increases quitting by 2-3X.
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Enhanced Recovery Protocol Associated with Decreased 3-Month Opioid Use Following Thoracic Surgeryby Raymond J Strobel on July 2, 2022
CONCLUSIONS: There is a high burden of prolonged opioid use following elective thoracic surgery. Participation in a comprehensive ERP is associated with decreased opioid use 3 months postoperatively.
- Development of a WeChat-based Mobile Messaging Smoking Cessation Intervention for Chinese Immigrant Smokers: Qualitative Interview Studyby Nan Jiang on June 30, 2022
CONCLUSIONS: Mobile messages are well accepted by Chinese immigrant smokers. Research is needed to assess the feasibility, acceptability, and efficacy of WeChat mobile messaging smoking cessation interventions for promoting abstinence among Chinese immigrant smokers.
- Cardiovascular Risk Among Patients Who Smoke: Risk Profiles and Differences by Sexby Ingrid Allagbé on June 30, 2022
CONCLUSIONS: Women who smoked had a high burden of risk factors, especially obesity and elevated rates of lung diseases, and a lower abstinence rate, with more common anxiety‒depression symptoms. Men who smoked had a higher prevalence of cardiovascular disease, higher nicotine dependence, and coaddictions. These findings highlight the need to strengthen cardiovascular prevention strategies through comprehensive sex-tailored smoking-cessation interventions.
- Novel rapid-acting sublingual nicotine tablet as a cigarette substitution strategyby Jed E Rose on June 29, 2022
CONCLUSIONS: The novel SL tablet studied shows promise as a nicotine substitution strategy for tobacco harm reduction and smoking cessation treatment. Additional studies are warranted to further investigate the potential of this new approach.